Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 11/20 | 0.54 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.54 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17504764 | 0.80 | FOLH1 (0.58) | FOLH1GRM3NAALAD2 | |
| SCHEMBL17504769 | 0.79 | PLA2G2C (0.46) | FOLH1GRM3NAALAD2 | |
| SCHEMBL20214857 | 0.77 | FOLH1 (0.50) | FOLH1GRM3NAALAD2 | |
| SCHEMBL19220635 | 0.76 | PLA2G2C (0.43) | FOLH1GRM3NAALAD2 | |
| SCHEMBL21804872 | 0.75 | PPARD (0.44) | FOLH1GRM3NAALAD2 | |
| SCHEMBL8053866 | 0.74 | FOLH1 (0.59) | FOLH1GRM3NAALAD2 | |
| SCHEMBL26424133 | 0.74 | FOLH1 (0.39) | FOLH1GRM3NAALAD2 | |
| SCHEMBL6381682 | 0.73 | FOLH1 (0.78) | FOLH1GRM3NAALAD2 | |
| SCHEMBL17533526 | 0.72 | FOLH1 (0.47) | FOLH1GRM3NAALAD2 | |
| SCHEMBL4135913 | 0.71 | GRM3 (1.00) | FOLH1GRM3NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016022827-A1 | PRODRUGS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITOR | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-02-11 | — | — | WO | disclosed |