SCHEMBL20215746

SCHEMBL20215746

CC(C)[Si]1(C(C)C)OC[C@H]2O[C@@H](n3ccc(=O)[nH]c3=O)C(O)C2O[Si](C(C)C)(C(C)C)O1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ SLC28A1 O00337 1/20 0.44
▸ SLC28A2 O43868 1/20 0.44
▸ SLC29A1 Q99808 1/20 0.44
▸ SLC28A3 Q9HAS3 1/20 0.44
▸ P2RY2 P41231 11/20 0.40
▸ P2RY6 Q15077 6/20 0.40
▸ P2RY4 P51582 3/20 0.38
▸ P2RY14 Q15391 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9945539 1.00 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL9964306 1.00 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL1582511 1.00 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL9964305 1.00 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL705500 1.00 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL859968 1.00 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL25400489 0.89 SLC28A1 (0.35) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL16572007 0.89 SLC28A1 (0.35) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL12170354 0.89 SLC28A1 (0.35) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL17972429 0.89 SLC28A1 (0.35) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357767-A1 NOVEL NUCLEIC ACID MOLECULE INHIBITING EXPRESSION OF TARGET GENE BONAC CORPORATION (JP) 2023-11-09 — — US disclosed
US-20230105319-A1 PRODRUG INCORPORATED sgRNA SYNTHESIS CRISPR THERAPEUTICS AG (CH) 2023-04-06 — — US disclosed
EP-2691118-B1 PERFLUORINATED COMPOUNDS FOR THE NON-VIRAL TRANSFER OF NUCLEIC ACIDS SCHAEFER KONSTANZE (DE) 2019-05-01 — — EP disclosed
US-20190085013-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO UNIV EMORY (US) 2019-03-21 — — US disclosed
US-9988415-B2 Glycoside compound, method for producing thioether, ether, method for producing ether, method for producing glycoside compound, method for producing nucleic acid BONAC CORPORATION (JP) 2018-06-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357767-A1 NOVEL NUCLEIC ACID MOLECULE INHIBITING EXPRESSION OF TARGET GENE SNRPE, DDX21, DCLRE1B SLC28A1 479/4885SLC28A2 505/4885SLC29A1 704/4885
US-20190085013-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO PNP, NTPCR, TYMP SLC28A1 17/4885SLC28A2 23/4885SLC29A1 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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