SCHEMBL859968

SCHEMBL859968

CC(C)[Si]1(C(C)C)OC[C@H]2O[C@@H](n3ccc(=O)[nH]c3=O)[C@H](O)[C@@H]2O[Si](C(C)C)(C(C)C)O1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ SLC28A1 O00337 1/20 0.44
▸ SLC28A2 O43868 1/20 0.44
▸ SLC29A1 Q99808 1/20 0.44
▸ SLC28A3 Q9HAS3 1/20 0.44
▸ P2RY2 P41231 11/20 0.40
▸ P2RY6 Q15077 6/20 0.40
▸ P2RY4 P51582 3/20 0.38
▸ P2RY14 Q15391 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20215746 1.00 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL9945539 1.00 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL9964306 1.00 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL1582511 1.00 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL9964305 1.00 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL705500 1.00 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL25400489 0.89 SLC28A1 (0.35) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL16572007 0.89 SLC28A1 (0.35) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL12170354 0.89 SLC28A1 (0.35) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL17972429 0.89 SLC28A1 (0.35) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4721764-A1 DSRNA TARGETING LPA AND USE THEREOF Tuojie Biotech (Shanghai) Co., Ltd. (CN) 2026-04-08 — — EP disclosed
US-20250057867-A1 NUCLEOSIDE PHOSPHORAMIDATES GILEAD SCIENCES INC (US) 2025-02-20 — — US disclosed
WO-2025038971-A1 OLIGONUCLEOTIDES CONTAINING A LIGAND AT A NUCLEOBASE, 2' POSITION, OR 3' POSITION ADARX PHARMACEUTICALS, INC. (US) 2025-02-20 — — WO disclosed
EP-4405368-A1 2'-ALKYL OR 3'- ALKYL MODIFIED RIBOSE DERIVATIVES FOR USE IN THE IN-VIVO DELIVERY OF OLIGONUCLEOTIDES Sanegene Bio USA Inc. (US) 2024-07-31 — — EP disclosed
US-20230383287-A1 ACETYLATED RIBONUCLEIC ACIDS AND USES THEREOF HELIX NANOTECHNOLOGIES INC 2023-11-30 — — US disclosed
US-20230383287-A1 ACETYLATED RIBONUCLEIC ACIDS AND USES THEREOF HELIX NANOTECHNOLOGIES INC 2023-11-30 — — US disclosed
US-20230241224-A1 2'-ALKYL OR 3'- ALKYL MODIFIED RIBOSE DERIVATIVES AND METHODS OF USE SANEGENE BIO USA INC. 2023-08-03 — — US disclosed
US-20230241224-A1 2'-ALKYL OR 3'- ALKYL MODIFIED RIBOSE DERIVATIVES AND METHODS OF USE SANEGENE BIO USA INC. 2023-08-03 — — US disclosed
US-20230183746-A1 COMPOSITIONS FOR TRANSFER OF CARGO TO CELLS Sixfold Bioscience Ltd. (GB) 2023-06-15 — — US disclosed
WO-2023049258-A1 2'-ALKYL OR 3'- ALKYL MODIFIED RIBOSE DERIVATIVES FOR USE IN THE IN-VIVO DELIVERY OF OLIGONUCLEOTIDES SANEGENE BIO USA INC. (US) 2023-03-30 — — WO disclosed
US-5872232-A 2'-O-modified oligonucleotides ISIS PHARMACEUTICALS INC. (US) 1999-02-16 — — US disclosed
US-5866700-A Solid-phase synthesis of oligoribonucleotides HOECHST AKTIENGESELLSCHAFT (DE) 1999-02-02 — — US disclosed
US-5859221-A HYBRID DNA, RNA; NUCLEASE RESISTANT ISIS PHARMACEUTICALS, INC. (US) 1999-01-12 — — US disclosed
US-5808035-A OLIGOMER BIOSYNTHESIS USHER, DAVID A. 1998-09-15 — — US disclosed
US-5652358-A Solid-phase synthesis of oligoribonucleotides HOECHST AKTIENGESELLSCHAFT (DE) 1997-07-29 — — US disclosed
US-5639647-A USEFUL IN ENZYMETIC CLEAVAGE OF RNA OR SINGLE STRANDED DNA, AND ALSO AS ANTISENSE OLIGONUCLEOTIDES RIBOZYME PHARMACEUTICALS, INC. (US) 1997-06-17 — — US disclosed
US-5627053-A STABILIZATION OF OLIGONUCLEOTIDES, ANTISENSE MOLECULES AND FORMING ALLYL DERIVATIVES FROM TRITYL-SILYL DERIVATIVES RIBOZYME PHARMACEUTICALS, INC. (US) 1997-05-06 — — US disclosed
EP-0746614-A1 METHOD AND REAGENT FOR INHIBITING THE EXPRESSION OF DISEASE RELATED GENES RIBOZYME PHARMACEUTICALS, INC. (US) 1996-12-11 — — EP disclosed
WO-1995023225-A2 METHOD AND REAGENT FOR INHIBITING THE EXPRESSION OF DISEASE RELATED GENES RIBOZYME PHARMACEUTICALS, INC. (US) 1995-08-31 — — WO disclosed
EP-0661291-A1 Solid phase synthesis of oligoribonucleotide HOECHST AKTIENGESELLSCHAFT (DE) 1995-07-05 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230383287-A1 ACETYLATED RIBONUCLEIC ACIDS AND USES THEREOF NSUN2, NSUN3, ADAR SLC28A1 988/4885SLC28A2 719/4885SLC29A1 933/4885
US-20250057867-A1 NUCLEOSIDE PHOSPHORAMIDATES PNP, RNGTT, NSUN2 SLC28A1 59/4885SLC28A2 84/4885SLC29A1 36/4885
US-20230241224-A1 2'-ALKYL OR 3'- ALKYL MODIFIED RIBOSE DERIVATIVES AND METHODS OF USE PARP1, PARP2, CD38 SLC28A1 230/4885SLC28A2 149/4885SLC29A1 100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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