Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24903992 | 1.00 | ATM (0.34) | ATMALDH1A1EPHX2KDM4EL3MBTL1 | |
| SCHEMBL24767270 | 0.84 | ALDH1A1 (0.33) | ALDH1A1EPHX2 | |
| SCHEMBL18361594 | 0.84 | L3MBTL1 (0.40) | ALDH1A1EPHX2L3MBTL1 | |
| SCHEMBL15932514 | 0.82 | — | — | |
| SCHEMBL12853788 | 0.80 | ALDH1A1 (0.33) | ATMALDH1A1KDM4EOGA | |
| SCHEMBL18347980 | 0.79 | EPHX2 (0.36) | EPHX2 | |
| SCHEMBL18347961 | 0.79 | EPHX2 (0.36) | EPHX2 | |
| SCHEMBL3260696 | 0.77 | OGA (0.35) | ATMALDH1A1OGA | |
| SCHEMBL3260689 | 0.77 | OGA (0.35) | ATMALDH1A1OGA | |
| SCHEMBL3260694 | 0.77 | OGA (0.35) | ATMALDH1A1OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9988391-B2 | TBK/IKK inhibitor compounds and uses thereof | MERCK PATENT GMBH (DE) | 2018-06-05 | — | — | US | disclosed |