SCHEMBL20216907

SCHEMBL20216907

COCCCCCSCC(C)CO

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PRKD3 O94806 3/20 0.37
PRKCG P05129 3/20 0.37
PRKCB P05771 3/20 0.37
PRKCA P17252 3/20 0.37
PRKCH P24723 3/20 0.37
PRKCI P41743 3/20 0.37
PRKCE Q02156 3/20 0.37
PRKCQ Q04759 3/20 0.37
PRKCZ Q05513 3/20 0.37
PRKCD Q05655 3/20 0.37
PRKD1 Q15139 3/20 0.37
ALDH1A1 P00352 1/20 0.34
ROCK2 O75116 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25964880 0.86 PRKD3 (0.36) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL10491227 0.81 USP2 (0.38) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL11081240 0.79 PRKD3 (0.47) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL11080097 0.79 PRKD3 (0.47) PRKD3PRKCGPRKCBPRKCAPRKCH
Phosphoric Acid SCHEMBL11080532 0.75 FDPS (0.43) PRKD3PRKCGPRKCBPRKCAPRKCH
Phosphoric Acid SCHEMBL11083446 0.75 FDPS (0.43) PRKD3PRKCGPRKCBPRKCAPRKCH
Phosphoric Acid SCHEMBL11077163 0.75 FDPS (0.43) PRKD3PRKCGPRKCBPRKCAPRKCH
Phosphoric Acid SCHEMBL11081350 0.75 PRKD3 (0.42) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL11080134 0.74 ALDH1A1 (0.40) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL24649644 0.74 PRKD3 (0.34) PRKD3PRKCGPRKCBPRKCAPRKCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3129385-B1 NEOSORAPHENS AND THEIR USE IN THE TREATMENT OR PREVENTION OF A VIRAL INFECTION OR OF A TH17-ASSOCIATED INFLAMMATORY AND/OR AUTOIMMUNE DISEASE HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) 2018-06-06 EP disclosed