Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SLC5A7 | Q9GZV3 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20217564 | 0.95 | LMNA (0.43) | LMNAALDH1A1SLC5A7PKMOPRM1 | |
| SCHEMBL20217268 | 0.89 | MEN1 (0.47) | LMNAALDH1A1SLC5A7PKMOPRM1 | |
| SCHEMBL20217283 | 0.86 | CCR3 (0.42) | LMNAALDH1A1SLC5A7PKMOPRM1 | |
| SCHEMBL20217729 | 0.84 | F10 (0.44) | LMNAALDH1A1SLC5A7PKMROCK2 | |
| SCHEMBL20217304 | 0.84 | F10 (0.44) | LMNAALDH1A1SLC5A7PKMROCK2 | |
| SCHEMBL20217296 | 0.81 | TTK (0.50) | LMNAALDH1A1SLC5A7PKMOPRM1 | |
| SCHEMBL20217562 | 0.80 | LMNA (0.45) | LMNAALDH1A1OPRM1OPRD1KMT2A | |
| SCHEMBL20217221 | 0.80 | TTK (0.51) | LMNAALDH1A1SLC5A7PKMKMT2A | |
| SCHEMBL20217547 | 0.79 | POLB (0.41) | LMNAALDH1A1SLC5A7PKMKMT2A | |
| SCHEMBL14873369 | 0.79 | CYP3A4 (0.62) | LMNAALDH1A1SLC5A7PKMROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766352-B1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIV HEALTH NETWORK UHN (CA) | 2018-06-06 | — | — | EP | disclosed |