Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.41 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20217272 | 0.89 | KDM4E (0.49) | HRH3F2PRSS1KDM4EMAPT | |
| SCHEMBL20217290 | 0.85 | ALDH1A1 (0.49) | HRH3F10F2PRSS1PRSS2 | |
| SCHEMBL20217632 | 0.82 | CYP3A4 (0.52) | HRH3F10KDRMEN1KMT2A | |
| SCHEMBL20217504 | 0.82 | TTK (0.39) | HRH3F10F2PRSS1PRSS2 | |
| SCHEMBL20217594 | 0.82 | F10 (0.43) | HRH3F10F2PRSS1PRSS2 | |
| SCHEMBL20217340 | 0.81 | MEN1 (0.42) | HRH3F10F2PRSS1PRSS2 | |
| SCHEMBL20217221 | 0.81 | TTK (0.51) | F10F2PRSS1PRSS2F7 | |
| SCHEMBL20217260 | 0.80 | TTK (0.39) | HRH3F10F2PRSS1PRSS2 | |
| SCHEMBL20217315 | 0.80 | CYP3A4 (0.52) | F10KDR | |
| SCHEMBL20217144 | 0.79 | ALOX15 (0.42) | F10PRSS1KDM4EIDO1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766352-B1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIV HEALTH NETWORK UHN (CA) | 2018-06-06 | — | — | EP | disclosed |