Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20219693 | 0.92 | TLR8 (0.35) | — | |
| SCHEMBL20219459 | 0.85 | TLR8 (0.33) | CRHR1 | |
| SCHEMBL23472365 | 0.77 | TLR8 (0.45) | — | |
| SCHEMBL23472392 | 0.76 | CDK1 (0.36) | — | |
| SCHEMBL20386677 | 0.71 | KCNH2 (0.36) | CRHR1 | |
| SCHEMBL23472574 | 0.70 | ATM (0.38) | CRHR1 | |
| SCHEMBL20219653 | 0.70 | TLR8 (0.43) | — | |
| SCHEMBL20219416 | 0.69 | TLR7 (0.34) | CRHR1 | |
| SCHEMBL20219712 | 0.69 | TLR8 (0.46) | — | |
| SCHEMBL23472545 | 0.67 | KCNH2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3330257-A1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | Janssen Sciences Ireland UC (IE) | 2018-06-06 | — | — | EP | disclosed |