Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 17/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 11/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15470366 | 1.00 | L3MBTL1 (0.49) | L3MBTL1TLR8TLR7CYP1A2CYP2D6 | |
| SCHEMBL13195081 | 0.88 | L3MBTL1 (0.52) | L3MBTL1TLR8TLR7CYP1A2CYP2D6 | |
| SCHEMBL15470372 | 0.86 | L3MBTL1 (0.48) | L3MBTL1TLR8TLR7CYP1A2CYP2D6 | |
| SCHEMBL15470373 | 0.86 | L3MBTL1 (0.50) | L3MBTL1TLR8TLR7 | |
| SCHEMBL20219391 | 0.86 | TLR8 (0.35) | L3MBTL1TLR8TLR7 | |
| SCHEMBL13195698 | 0.83 | L3MBTL1 (0.57) | L3MBTL1TLR8TLR7CYP1A2CYP2D6 | |
| SCHEMBL13195825 | 0.83 | L3MBTL1 (0.57) | L3MBTL1TLR8TLR7 | |
| SCHEMBL13195687 | 0.83 | L3MBTL1 (0.57) | L3MBTL1TLR8TLR7CYP1A2 | |
| SCHEMBL20219474 | 0.82 | TLR8 (0.33) | L3MBTL1TLR8TLR7CYP1A2 | |
| SCHEMBL13195741 | 0.82 | TLR8 (0.59) | L3MBTL1TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |
| EP-3330257-A1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | Janssen Sciences Ireland UC (IE) | 2018-06-06 | — | — | EP | disclosed |