SCHEMBL20220156

SCHEMBL20220156

Oc1ccc(-c2cc(-c3ccccc3)nc(-c3ccccc3)n2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 10/20 1.00
KMT2A Q03164 10/20 1.00
NTSR1 P30989 2/20 1.00
MAPT P10636 8/20 0.66
ALDH1A1 P00352 8/20 0.66
HPGD P15428 8/20 0.66
ADORA2A P29274 2/20 0.57
ADORA1 P30542 2/20 0.57
MMP3 P08254 1/20 0.56
BCL2L1 Q07817 1/20 0.56
KDM4E B2RXH2 4/20 0.56
LMNA P02545 3/20 0.56
GLA P06280 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
RXFP1 Q9HBX9 1/20 0.56
CDC7 O00311 1/20 0.56
CYP2C19 P33261 1/20 0.56
HTT P42858 1/20 0.55
ATM Q13315 1/20 0.55
POLB P06746 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30032821 0.94 MEN1 (0.88) MEN1KMT2ANTSR1MAPTALDH1A1
SCHEMBL17367816 0.89 MEN1 (0.79) MEN1KMT2ANTSR1MAPTALDH1A1
SCHEMBL17970040 0.89 MEN1 (0.79) MEN1KMT2ANTSR1MAPTALDH1A1
SCHEMBL17367827 0.89 MEN1 (0.79) MEN1KMT2ANTSR1MAPTALDH1A1
SCHEMBL13492075 0.87 MEN1 (0.76) MEN1KMT2ANTSR1MAPTALDH1A1
SCHEMBL9920584 0.87 MEN1 (0.76) MEN1KMT2ANTSR1MAPTALDH1A1
SCHEMBL12306206 0.87 MEN1 (0.76) MEN1KMT2ANTSR1MAPTALDH1A1
SCHEMBL13665827 0.87 MEN1 (0.76) MEN1KMT2ANTSR1MAPTALDH1A1
SCHEMBL17725321 0.87 MEN1 (0.76) MEN1KMT2ANTSR1MAPTALDH1A1
SCHEMBL10051312 0.87 MEN1 (0.76) MEN1KMT2ANTSR1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11730009-B2 Compound and organic light-emitting element comprising same LG CHEM, LTD. 2023-08-15 US disclosed
US-11730009-B2 Compound and organic light-emitting element comprising same LG CHEM, LTD. 2023-08-15 US disclosed
EP-3330265-B1 COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2020-04-15 EP disclosed
EP-3330265-A1 COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2018-06-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11730009-B2 Compound and organic light-emitting element comprising same CRY2, CRY1, NR2E3 MEN1 673/4885KMT2A 551/4885NTSR1 4796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.