SCHEMBL20220161

SCHEMBL20220161

c1ccc(-c2cc(-c3ccc(Oc4ccc(-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)cc4)cc3)nc(-c3ccccc3)n2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.67
KMT2A Q03164 7/20 0.67
MAPT P10636 6/20 0.67
HPGD P15428 6/20 0.67
ALDH1A1 P00352 5/20 0.67
MAPK1 P28482 2/20 0.66
TDP1 Q9NUW8 1/20 0.66
NTSR1 P30989 1/20 0.61
MAOA P21397 3/20 0.59
MAOB P27338 3/20 0.59
KDM4E B2RXH2 2/20 0.57
GLA P06280 2/20 0.57
LMNA P02545 1/20 0.57
MCL1 Q07820 2/20 0.54
ADORA2A P29274 1/20 0.53
ADORA1 P30542 1/20 0.53
XDH P47989 1/20 0.50
BRD4 O60885 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21882522 1.00 MEN1 (0.67) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL21882405 0.98 MEN1 (0.65) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL20220304 0.98 MAPK1 (0.68) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL20220275 0.98 MAPK1 (0.68) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL21882458 0.98 MAPK1 (0.68) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL21882404 0.96 MAPK1 (0.66) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL25985402 0.96 MAPK1 (0.66) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL21882436 0.96 MAPK1 (0.66) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL21882438 0.96 MAPK1 (0.66) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL22330039 0.92 MAPK1 (0.61) MEN1KMT2AMAPTHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11730009-B2 Compound and organic light-emitting element comprising same LG CHEM, LTD. 2023-08-15 US disclosed
US-11730009-B2 Compound and organic light-emitting element comprising same LG CHEM, LTD. 2023-08-15 US disclosed
EP-3330265-B1 COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2020-04-15 EP disclosed
EP-3330265-A1 COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2018-06-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11730009-B2 Compound and organic light-emitting element comprising same CRY2, CRY1, NR2E3 MEN1 673/4885KMT2A 551/4885MAPT 370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.