Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHB3 | P54753 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20220482 | 0.86 | EPHB3 (0.49) | EPHB3L3MBTL1FLT3 | |
| SCHEMBL20220335 | 0.86 | EPHB3 (0.58) | EPHB3ALDH1A1POLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL20220418 | 0.83 | EPHB3 (0.54) | EPHB3ALDH1A1KDM4EUSP2TSHR | |
| SCHEMBL16291892 | 0.81 | NTRK1 (0.52) | — | |
| SCHEMBL15039745 | 0.81 | NTRK1 (0.52) | — | |
| SCHEMBL20220520 | 0.80 | EPHB3 (0.60) | EPHB3ALDH1A1FLT3KDM4EUSP2 | |
| SCHEMBL20220360 | 0.80 | EPHB3 (0.53) | EPHB3FLT3PIK3CA | |
| SCHEMBL20220334 | 0.79 | EPHB3 (0.59) | EPHB3ALDH1A1SMN1; SMN2FLT3KDM4E | |
| SCHEMBL19562773 | 0.78 | EPHB3 (0.59) | EPHB3ALDH1A1FLT3KDM4ETSHR | |
| SCHEMBL20220560 | 0.78 | EPHB3 (0.58) | EPHB3ALDH1A1FLT3KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791138-B1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE AS TROPOMYOSIN RECEPTOR KINASE (TRK) INHIBITORS | Dr Reddys Laboratories Ltd (IN) | 2018-06-06 | — | — | EP | disclosed |