Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 12/20 | 0.41 |
| ▸ | ACACA | Q13085 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14945739 | 0.92 | ACACB (0.51) | ACACBADORA2BACACA | |
| SCHEMBL14945146 | 0.87 | ACACB (0.53) | ACACBADORA2BACACA | |
| SCHEMBL14945733 | 0.84 | ACACB (0.55) | ACACBADORA2BACACAMEN1KMT2A | |
| SCHEMBL14945774 | 0.83 | ACACB (0.47) | ACACBADORA2BACACAMEN1KMT2A | |
| SCHEMBL14945175 | 0.82 | ACACB (0.52) | ACACBADORA2BACACA | |
| SCHEMBL14950652 | 0.80 | ACACB (0.56) | ACACBADORA2BACACA | |
| SCHEMBL14945319 | 0.78 | ACACB (0.61) | ACACBADORA2BACACA | |
| SCHEMBL14945145 | 0.78 | ACACA (0.59) | ACACBACACA | |
| SCHEMBL14945491 | 0.78 | ADORA2B (0.54) | ACACBADORA2BACACA | |
| SCHEMBL20651073 | 0.77 | ACACB (0.51) | ACACBADORA2BACACAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3329919-A1 | ACC INHIBITORS AND USES THEREOF | Gilead Apollo, LLC (US) | 2018-06-06 | — | — | EP | disclosed |