Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 10/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 9/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21548277 | 0.86 | NPY5R (0.45) | LTB4RLTB4R2NPY5ROPRM1OPRD1 | |
| SCHEMBL4144964 | 0.79 | LTB4R (0.56) | LTB4RLTB4R2NPY5ROPRM1KMT2A | |
| SCHEMBL30443271 | 0.77 | KMT2A (0.53) | OPRM1KMT2AMLYCDALOX5 | |
| SCHEMBL8274813 | 0.76 | LTB4R (0.54) | LTB4RLTB4R2KMT2AALOX5 | |
| SCHEMBL14191750 | 0.73 | L3MBTL1 (0.49) | OPRM1KMT2AALOX5 | |
| SCHEMBL13034052 | 0.72 | LTB4R (0.52) | LTB4RLTB4R2NPY5RKMT2AMLYCD | |
| SCHEMBL2097870 | 0.71 | NPY5R (0.56) | LTB4RLTB4R2NPY5RKMT2AMLYCD | |
| SCHEMBL15806390 | 0.71 | KCNH2 (0.59) | — | |
| SCHEMBL1520363 | 0.70 | KMT2A (0.59) | LTB4RLTB4R2NPY5RKMT2AMLYCD | |
| SCHEMBL7661443 | 0.70 | NPC1 (0.52) | KMT2AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3329919-A1 | ACC INHIBITORS AND USES THEREOF | Gilead Apollo, LLC (US) | 2018-06-06 | — | — | EP | disclosed |