Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 16/20 | 0.61 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16855470 | 1.00 | ADRA1A (0.61) | ADRA1ADGAT2TMEM97SIGMAR1 | |
| SCHEMBL20312054 | 0.88 | ADRA1A (0.61) | ADRA1ADGAT2 | |
| SCHEMBL20220518 | 0.87 | ADRA1A (0.80) | ADRA1ATMEM97SIGMAR1 | |
| SCHEMBL16824536 | 0.87 | ADRA1A (0.80) | ADRA1ATMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL18186152 | 0.86 | ADRA1A (0.78) | ADRA1ATMEM97SIGMAR1 | |
| SCHEMBL18744229 | 0.81 | ADRA1A (0.66) | ADRA1A | |
| SCHEMBL16846262 | 0.76 | ADRA1A (1.00) | ADRA1A | |
| SCHEMBL30823772 | 0.75 | PRMT5 (0.53) | ADRA1A | |
| SCHEMBL22418693 | 0.75 | PRMT5 (0.53) | ADRA1A | |
| SCHEMBL20052796 | 0.74 | ADRA1A (0.79) | ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3329920-A2 | ADRENORECEPTOR ALPHA2C RECEPTOR ANTAGONISTS | Bayer Pharma Aktiengesellschaft (DE) | 2018-06-06 | — | — | EP | disclosed |