Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 19/20 | 0.66 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18145308 | 0.86 | ADRA1A (0.69) | ADRA1A | |
| SCHEMBL20220613 | 0.81 | ADRA1A (0.61) | ADRA1A | |
| SCHEMBL16855470 | 0.81 | ADRA1A (0.61) | ADRA1A | |
| SCHEMBL16854317 | 0.79 | ADRA1A (1.00) | ADRA1A | |
| SCHEMBL16824339 | 0.78 | ROCK2 (0.40) | ADRA1A | |
| SCHEMBL1367212 | 0.78 | ROCK2 (0.40) | ADRA1A | |
| SCHEMBL16827278 | 0.75 | ADRA1A (1.00) | ADRA1AL3MBTL3L3MBTL1 | |
| SCHEMBL16854293 | 0.74 | ADRA1A (1.00) | ADRA1AL3MBTL3L3MBTL1 | |
| SCHEMBL16824342 | 0.73 | CASP3 (0.38) | — | |
| SCHEMBL7960845 | 0.73 | MEN1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624199-B2 | Substituted bipiperidinyl derivatives | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-04-18 | — | — | US | disclosed |
| US-9624199-B2 | Substituted bipiperidinyl derivatives | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-04-18 | — | — | US | disclosed |