SCHEMBL2022136

SCHEMBL2022136

CC[Si](OC)(OC)OC(c1ccccc1)S(=O)(=O)Cl

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.33
▸ ALDH1A1 P00352 2/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32
▸ KMT2A Q03164 1/20 0.31
▸ PSIP1 O75475 1/20 0.31
▸ MMP13 P45452 1/20 0.31
▸ CCR5 P51681 1/20 0.31
▸ POLB P06746 1/20 0.30
▸ ATM Q13315 1/20 0.30
▸ CA12 O43570 1/20 0.30
▸ CA7 P43166 1/20 0.30
▸ CA9 Q16790 1/20 0.30
▸ CA14 Q9ULX7 1/20 0.30
▸ KCNA5 P22460 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27476570 0.75 KMT2A (0.39) LMNAALDH1A1HSD17B10TDP1KMT2A
SCHEMBL6890319 0.74 LMNA (0.33) LMNAKMT2APOLB
SCHEMBL28319153 0.72 DPP4 (0.35) LMNAHSD17B10
SCHEMBL27601773 0.72 LMNA (0.42) LMNAKMT2APOLB
SCHEMBL29111579 0.72 LMNA (0.34) LMNAKMT2APOLBATM
SCHEMBL30539308 0.70 SLC6A2 (0.33) LMNAKMT2AMMP13
SCHEMBL27844000 0.69 KDM4E (0.33) LMNAALDH1A1HSD17B10TDP1KMT2A
SCHEMBL10567481 0.65 CA4 (0.42) LMNA
SCHEMBL1608663 0.65 CA4 (0.42) LMNA
Chlorobenzene SCHEMBL27723164 0.65 TSHR (0.48) LMNAALDH1A1TDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2343544-B1 Method for analyzing hemoglobin by electrophoresis ARKRAY INC (JP) 2015-03-11 — — EP disclosed
US-8702941-B2 Method of analyzing hemoglobin by electrophoresis ARKARY, Inc. (JP) 2014-04-22 — — US disclosed
EP-2343544-A1 Method for analyzing hemoglobin by electrophoresis Arkray, Inc. (JP) 2011-07-13 — — EP disclosed
US-20110155573-A1 METHOD OF ANALYZING HEMOGLOBIN BY ELECTROPHORESIS ARKRAY, INC. (JP) 2011-06-30 — — US disclosed
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