SCHEMBL20224271

SCHEMBL20224271

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4c(c3)C3(c5ccccc5-c5ccccc5-4)c4ccccc4-c4c3ccc3c4oc4ccccc43)n2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.36
MAPT P10636 10/20 0.34
KMT2A Q03164 6/20 0.34
LMNA P02545 5/20 0.34
TSHR P16473 4/20 0.34
POLB P06746 3/20 0.34
HTT P42858 1/20 0.34
ALDH1A1 P00352 8/20 0.33
KDM4E B2RXH2 3/20 0.33
HPGD P15428 3/20 0.33
NPSR1 Q6W5P4 3/20 0.32
HSD17B10 Q99714 3/20 0.32
USP2 O75604 1/20 0.32
PGR P06401 1/20 0.31
MEN1 O00255 5/20 0.31
MAPK1 P28482 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20224293 0.99 ALOX5 (0.35) ALOX5MAPTKMT2ALMNATSHR
SCHEMBL18156835 0.99 ALOX5 (0.36) ALOX5MAPTKMT2ALMNATSHR
SCHEMBL16855610 0.99 ALOX5 (0.36) ALOX5MAPTKMT2ALMNATSHR
SCHEMBL14681706 0.99 ALOX5 (0.36) ALOX5MAPTKMT2ALMNATSHR
SCHEMBL18156717 0.99 ALOX5 (0.36) ALOX5MAPTKMT2ALMNATSHR
SCHEMBL18732043 0.98 ALOX5 (0.36) ALOX5MAPTKMT2ALMNATSHR
SCHEMBL20224300 0.96 ALOX5 (0.35) ALOX5MAPTKMT2ALMNATSHR
SCHEMBL18156704 0.96 ALOX5 (0.37) ALOX5MAPTKMT2ALMNATSHR
SCHEMBL18156681 0.96 ALOX5 (0.37) ALOX5MAPTKMT2ALMNATSHR
SCHEMBL18156720 0.95 MAPT (0.36) ALOX5MAPTKMT2ALMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11183641-B2 Composition for an organic electronic device and organic electronic device using the same SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) 2021-11-23 US disclosed
US-20180159044-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2018-06-07 US disclosed
US-20180159044-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2018-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11183641-B2 Composition for an organic electronic device and organic electronic device using the same ORC3, ZYX, ESR1 ALOX5 2066/4885MAPT 4073/4885KMT2A 1063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.