Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11439088 | 0.94 | FUT7 (0.38) | GRIN2DGRIN2AGRIN2BGRIN2CGPR84 | |
| SCHEMBL14021986 | 0.86 | NOS3 (0.33) | — | |
| SCHEMBL12197971 | 0.76 | TDP1 (0.62) | TDP1L3MBTL1CYP2A6HRH3 | |
| SCHEMBL21157758 | 0.76 | GRM2 (0.39) | GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL21946504 | 0.76 | TDP1 (0.34) | TDP1L3MBTL1CYP2A6 | |
| Bromide SCHEMBL18838899 | 0.75 | TDP1 (0.61) | TDP1L3MBTL1CYP2A6HRH3 | |
| SCHEMBL12495594 | 0.75 | L3MBTL1 (0.50) | TDP1L3MBTL1LMNAPKMHRH3 | |
| SCHEMBL10770756 | 0.74 | SLC6A2 (0.41) | LMNACYP2A6HRH3 | |
| SCHEMBL3169642 | 0.74 | HRH1 (0.50) | GRIN2DGRIN2AGRIN2BGRIN2CTDP1 | |
| SCHEMBL10518610 | 0.74 | TYR (0.36) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180154332-A1 | HIGH PURITY CHROMATOGRAPHIC MATERIALS COMPRISING ION PAIRED-BONDED PHASES FOR SUPERCRITICAL FLUID CHROMATOGRAPHY | WATERS TECHNOLOGIES CORPORATION | 2018-06-07 | — | — | US | disclosed |