Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | ATM | Q13315 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20225516 | 0.82 | SMN1; SMN2 (0.42) | SMN1; SMN2POLBGPR55ALDH1A1ATM | |
| SCHEMBL359232 | 0.78 | ATM (0.52) | SMN1; SMN2POLBGPR55ALDH1A1ATM | |
| SCHEMBL15937720 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2POLBGPR55ALDH1A1ATM | |
| SCHEMBL12958498 | 0.75 | SMN1; SMN2 (0.38) | SMN1; SMN2POLBGPR55ALDH1A1ATM | |
| SCHEMBL3691449 | 0.74 | ALDH1A1 (0.55) | SMN1; SMN2POLBGPR55ALDH1A1ATM | |
| SCHEMBL14081321 | 0.73 | ATM (0.48) | SMN1; SMN2POLBGPR55ALDH1A1ATM | |
| SCHEMBL16435784 | 0.69 | SMN1; SMN2 (0.41) | SMN1; SMN2POLBGPR55ALDH1A1ATM | |
| SCHEMBL16435779 | 0.69 | ATM (0.41) | SMN1; SMN2POLBGPR55ALDH1A1ATM | |
| SCHEMBL16435782 | 0.69 | POLB (0.39) | SMN1; SMN2POLBGPR55ALDH1A1ATM | |
| SCHEMBL12958395 | 0.68 | POLB (0.38) | SMN1; SMN2POLBGPR55ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180157183-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2018-06-07 | — | — | US | disclosed |
| US-20180157183-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2018-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180157183-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KEAP1, RAD54L, ARL1 | SMN1; SMN2 4819/4885POLB 2846/4885GPR55 3227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.