Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 19/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27547969 | 0.91 | TOP1 (0.73) | TOP1MEN1KMT2A | |
| SCHEMBL27731508 | 0.88 | TOP1 (0.78) | TOP1MEN1KMT2A | |
| SCHEMBL27699980 | 0.87 | TOP1 (0.77) | TOP1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL27699979 | 0.86 | TOP1 (0.76) | TOP1MEN1KMT2A | |
| SCHEMBL4449734 | 0.86 | TOP1 (0.77) | TOP1MEN1KMT2A | |
| SCHEMBL27731507 | 0.86 | TOP1 (0.74) | TOP1MEN1KMT2A | |
| SCHEMBL27752128 | 0.85 | TOP1 (0.74) | TOP1MEN1KMT2A | |
| SCHEMBL21450567 | 0.83 | TOP1 (1.00) | TOP1 | |
| SCHEMBL21450564 | 0.83 | TOP1 (1.00) | TOP1 | |
| SCHEMBL8198356 | 0.82 | TOP1 (0.76) | TOP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2515898-A1 | ANTICANCER COMBINATION OF ARTEMISININ-BASED DRUGS AND OTHER CHEMOTHERAPEUTIC AGENTS | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. (IT) | 2012-10-31 | — | — | EP | claimed |
| US-20120258181-A1 | ANTICANCER COMBINATION OF ARTEMISININ-BASED DRUGS AND OTHER CHEMOTHERAPEUTIC AGENTS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2012-10-11 | — | — | US | claimed |
| WO-2011076547-A1 | ANTICANCER COMBINATION OF ARTEMISININ-BASED DRUGS AND OTHER CHEMOTHERAPEUTIC AGENTS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2011-06-30 | — | — | WO | claimed |
| EP-2515898-A1 | ANTICANCER COMBINATION OF ARTEMISININ-BASED DRUGS AND OTHER CHEMOTHERAPEUTIC AGENTS | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. (IT) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011076547-A1 | ANTICANCER COMBINATION OF ARTEMISININ-BASED DRUGS AND OTHER CHEMOTHERAPEUTIC AGENTS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2011-06-30 | — | — | WO | disclosed |