Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | MEN1 | O00255 | 6/20 | 0.78 |
| ▸ | TP53 | P04637 | 2/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.66 |
| ▸ | RECQL | P46063 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.60 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.60 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20228784 | 0.92 | KMT2A (0.85) | KMT2AMEN1TP53KDM4EALDH1A1 | |
| SCHEMBL18826078 | 0.81 | KMT2A (0.76) | KMT2AMEN1TP53KDM4EALDH1A1 | |
| SCHEMBL20228787 | 0.78 | ALDH1A1 (0.70) | KMT2AMEN1TP53KDM4EALDH1A1 | |
| SCHEMBL13440499 | 0.77 | ALDH1A1 (0.74) | KMT2AMEN1TP53KDM4EALDH1A1 | |
| SCHEMBL12682848 | 0.76 | ALDH1A1 (0.70) | KMT2AMEN1TP53KDM4EALDH1A1 | |
| SCHEMBL20228785 | 0.76 | ALDH1A1 (0.68) | KMT2AMEN1TP53KDM4EALDH1A1 | |
| SCHEMBL13856555 | 0.76 | POLB (1.00) | KMT2AMEN1TP53KDM4EALDH1A1 | |
| SCHEMBL20228921 | 0.76 | KMT2A (0.66) | KMT2AMEN1TP53KDM4EALDH1A1 | |
| SCHEMBL6037643 | 0.75 | TGM2 (0.74) | KMT2AMEN1TP53KDM4EALDH1A1 | |
| SCHEMBL19079839 | 0.75 | KDM4E (0.73) | KMT2AMEN1TP53KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12370169-B2 | Small molecule Bcl-2 functional converters as cancer therapeutics | OREGON STATE UNIVERSITY (US) | 2025-07-29 | — | — | US | claimed |
| US-20230129487-A1 | SMALL MOLECULE BCL-2 FUNCTIONAL CONVERTERS AS CANCER THERAPEUTICS | OREGON STATE UNIVERSITY (US) | 2023-04-27 | — | — | US | claimed |
| US-20260014115-A1 | SMALL MOLECULE BCL-2 FUNCTIONAL CONVERTERS AS CANCER THERAPEUTICS | OREGON STATE UNIVERSITY (US) | 2026-01-15 | — | — | US | disclosed |
| US-12370169-B2 | Small molecule Bcl-2 functional converters as cancer therapeutics | OREGON STATE UNIVERSITY (US) | 2025-07-29 | — | — | US | disclosed |
| US-20230129487-A1 | SMALL MOLECULE BCL-2 FUNCTIONAL CONVERTERS AS CANCER THERAPEUTICS | OREGON STATE UNIVERSITY (US) | 2023-04-27 | — | — | US | disclosed |
| US-20230129487-A1 | SMALL MOLECULE BCL-2 FUNCTIONAL CONVERTERS AS CANCER THERAPEUTICS | OREGON STATE UNIVERSITY (US) | 2023-04-27 | — | — | US | disclosed |
| US-20230129487-A1 | SMALL MOLECULE BCL-2 FUNCTIONAL CONVERTERS AS CANCER THERAPEUTICS | OREGON STATE UNIVERSITY (US) | 2023-04-27 | — | — | US | disclosed |
| US-11419843-B2 | Small molecule BCL-2 functional converters as cancer therapeutics | OREGON STATE UNIVERSITY (US) | 2022-08-23 | — | — | US | disclosed |
| US-11419843-B2 | Small molecule BCL-2 functional converters as cancer therapeutics | OREGON STATE UNIVERSITY (US) | 2022-08-23 | — | — | US | disclosed |
| US-20190336469-A1 | SMALL MOLECULE BCL-2 FUNCTIONAL CONVERTERS AS CANCER THERAPEUTICS | OREGON STATE UNIVERSITY (US) | 2019-11-07 | — | — | US | disclosed |
| WO-2018102766-A2 | SMALL MOLECULE BCL-2 FUNCTIONAL CONVERTERS AS CANCER THERAPEUTICS | OREGON STATE UNIVERSITY (US) | 2018-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260014115-A1 | SMALL MOLECULE BCL-2 FUNCTIONAL CONVERTERS AS CANCER THERAPEUTICS | BCL2, BAX, BCL2A1 | KMT2A 3281/4885MEN1 2030/4885TP53 27/4885 |
| US-12370169-B2 | Small molecule Bcl-2 functional converters as cancer therapeutics | BCL2, BCL2L1, BCL2L13 | KMT2A 3078/4885MEN1 2362/4885TP53 25/4885 |
| US-11419843-B2 | Small molecule BCL-2 functional converters as cancer therapeutics | BCL2, BCL2L1, BCL2L13 | KMT2A 3078/4885MEN1 2362/4885TP53 25/4885 |
| US-20190336469-A1 | SMALL MOLECULE BCL-2 FUNCTIONAL CONVERTERS AS CANCER THERAPEUTICS | BCL2, BCL2L1, BCL2L13 | KMT2A 3078/4885MEN1 2362/4885TP53 25/4885 |
| US-20230129487-A1 | SMALL MOLECULE BCL-2 FUNCTIONAL CONVERTERS AS CANCER THERAPEUTICS | BCL2, BCL2L1, BCL2L13 | KMT2A 3078/4885MEN1 2362/4885TP53 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.