SCHEMBL20229409

SCHEMBL20229409

O=C(c1ccccc1)c1ccc2c3ccccc3n(-c3ccccc3)c2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.56
ATM Q13315 2/20 0.56
KDM4E B2RXH2 2/20 0.56
CNR2 P34972 1/20 0.48
ALDH1A1 P00352 4/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
GLA P06280 1/20 0.48
TDP1 Q9NUW8 1/20 0.47
PTPN1 P18031 1/20 0.46
SRD5A2 P31213 1/20 0.43
POLB P06746 2/20 0.42
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
HPGD P15428 2/20 0.41
LMNA P02545 2/20 0.41
MAPT P10636 2/20 0.41
MAT2A P31153 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12117427 0.92 ALDH1A1 (0.49) L3MBTL1ATMKDM4ECNR2ALDH1A1
SCHEMBL12117362 0.91 CNR2 (0.49) L3MBTL1ATMKDM4ECNR2ALDH1A1
SCHEMBL17850894 0.89 L3MBTL1 (0.52) L3MBTL1ATMKDM4ECNR2ALDH1A1
SCHEMBL13780969 0.89 L3MBTL1 (0.57) L3MBTL1ATMKDM4ECNR2ALDH1A1
SCHEMBL31356468 0.89 L3MBTL1 (0.61) L3MBTL1ATMKDM4ECNR2ALDH1A1
SCHEMBL3331741 0.89 L3MBTL1 (0.61) L3MBTL1ATMKDM4ECNR2ALDH1A1
SCHEMBL23181631 0.88 L3MBTL1 (0.56) L3MBTL1ATMKDM4ECNR2ALDH1A1
SCHEMBL13780972 0.87 L3MBTL1 (0.55) L3MBTL1ATMKDM4ECNR2ALDH1A1
SCHEMBL13011123 0.87 KDM4E (0.60) L3MBTL1ATMKDM4EALDH1A1TDP1
SCHEMBL31464191 0.87 KDM4E (0.60) L3MBTL1ATMKDM4EALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11174427-B2 Aromatic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2021-11-16 US disclosed
US-20180155617-A1 AROMATIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-07 US disclosed