Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HINT1 | P49773 | 3/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20217051 | 0.91 | TAS1R3 (0.53) | POLA1TAS1R3TAS1R1KDM4EALDH1A1 | |
| SCHEMBL8540848 | 0.78 | POLA1 (0.69) | POLA1KDM4E | |
| SCHEMBL15720909 | 0.78 | POLA1 (0.69) | POLA1KDM4E | |
| SCHEMBL23648123 | 0.78 | POLA1 (0.69) | POLA1KDM4E | |
| SCHEMBL6283863 | 0.78 | POLA1 (0.69) | POLA1KDM4E | |
| SCHEMBL26455488 | 0.78 | TAS1R3 (0.54) | POLA1TAS1R3TAS1R1KDM4EALDH1A1 | |
| SCHEMBL6560800 | 0.75 | TAS1R3 (0.56) | POLA1TAS1R3TAS1R1KDM4EALDH1A1 | |
| SCHEMBL19325459 | 0.75 | TAS1R3 (0.56) | POLA1TAS1R3TAS1R1KDM4EALDH1A1 | |
| SCHEMBL26455476 | 0.74 | TAS1R3 (0.52) | POLA1TAS1R3TAS1R1KDM4EALDH1A1 | |
| SCHEMBL9141785 | 0.73 | KDM4E (0.51) | POLA1TAS1R3TAS1R1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018099946-A1 | NOVEL BICYCLIC NUCLEOSIDES AND OLIGOMERS PREPARED THEREFROM | Universität Bern (CH) | 2018-06-07 | — | — | WO | disclosed |