SCHEMBL20230751

SCHEMBL20230751

CC1(C)c2ccc(-c3ccc(C#N)cc3C#N)cc2Oc2cc(N3c4ccccc4C(C)(C)c4ccccc43)ccc21

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PGR P06401 3/20 0.39
AR P10275 1/20 0.34
STS P08842 1/20 0.33
ALK Q9UM73 1/20 0.32
PDK2 Q15119 2/20 0.30
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22871811 0.94 PGR (0.39) PGRARSTSPDK2USP2
SCHEMBL20230660 0.88 PGR (0.41) PGRARSTSALKPDK2
SCHEMBL20230749 0.87 PGR (0.40) PGRPDK2USP2
SCHEMBL19344995 0.86 PGR (0.48) PGRARSTSALKPDK2
SCHEMBL22871829 0.86 PGR (0.36) PGRARSTS
SCHEMBL20230683 0.84 PGR (0.42) PGRARSTSPDK2
SCHEMBL22871859 0.82 PGR (0.39) PGRARSTSPDK2
SCHEMBL22871808 0.81 PGR (0.40) PGRPDK2USP2
SCHEMBL19345027 0.79 STS (0.42) PGRSTSUSP2
SCHEMBL20230599 0.79 STS (0.35) PGRSTSPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10892423-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2021-01-12 US disclosed
US-20180159050-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-07 US disclosed
US-20180159050-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180159050-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CCNE2, CCNT1 PGR 2842/4885AR 3636/4885STS 4648/4885
US-10892423-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CCNE2, CCNT1 PGR 2842/4885AR 3636/4885STS 4648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.