⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13424994 | 0.91 | — | — | |
| SCHEMBL9119548 | 0.85 | MAPK1 (0.55) | — | |
| SCHEMBL9118802 | 0.85 | MAPK1 (0.55) | — | |
| SCHEMBL9689041 | 0.83 | CYSLTR2 (0.53) | — | |
| SCHEMBL9689591 | 0.83 | CYSLTR2 (0.56) | — | |
| SCHEMBL9689399 | 0.82 | CYSLTR2 (0.52) | — | |
| SCHEMBL9688179 | 0.82 | — | — | |
| SCHEMBL9222120 | 0.81 | CYSLTR2 (0.55) | — | |
| SCHEMBL12927207 | 0.81 | PLA2G2A (0.50) | — | |
| Acetic Acid SCHEMBL4252301 | 0.81 | CYSLTR2 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516401-A1 | IMPROVED PROCESS FOR THE PREPARATION OF MONTELUKAST AND SALTS THEREOF | Pharmathen S.A. (GR) | 2012-10-31 | — | — | EP | claimed |
| US-20120259121-A1 | PROCESS FOR THE PREPARATION OF MONTELUKAST AND SALTS THEREOF | PHARMATHEN S.A. (GR) | 2012-10-11 | — | — | US | claimed |
| WO-2011076237-A1 | IMPROVED PROCESS FOR THE PREPARATION OF MONTELUKAST AND SALTS THEREOF | PHARMATHEN S.A. (GR) | 2011-06-30 | — | — | WO | claimed |
| EP-2516401-A1 | IMPROVED PROCESS FOR THE PREPARATION OF MONTELUKAST AND SALTS THEREOF | Pharmathen S.A. (GR) | 2012-10-31 | — | — | EP | disclosed |
| US-20120259121-A1 | PROCESS FOR THE PREPARATION OF MONTELUKAST AND SALTS THEREOF | PHARMATHEN S.A. (GR) | 2012-10-11 | — | — | US | disclosed |
| US-8115004-B2 | Process for pure montelukast sodium through pure intermediates as well as amine salts | MSN LABORATORIES LIMITED (IN) | 2012-02-14 | — | — | US | disclosed |
| US-8115004-B2 | Process for pure montelukast sodium through pure intermediates as well as amine salts | MSN LABORATORIES LIMITED (IN) | 2012-02-14 | — | — | US | disclosed |
| WO-2011076237-A1 | IMPROVED PROCESS FOR THE PREPARATION OF MONTELUKAST AND SALTS THEREOF | PHARMATHEN S.A. (GR) | 2011-06-30 | — | — | WO | disclosed |
| WO-2008062478-A2 | IMPROVED PROCESS FOR PURE MONTELUKAST SODIUM THROUGH PURE INTERMEDIATES AS WELL AS NOVEL AMINE SALTS | SATYANARAYANA REDDY MANNE (IN) | 2008-05-29 | — | — | WO | disclosed |