SCHEMBL12927207

SCHEMBL12927207

COC(=O)c1ccccc1CC[C@H](O)c1cccc(CCc2ccc3ccc(Cl)cc3n2)c1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ PLA2G2A P14555 1/20 0.50
▸ LTB4R Q15722 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13015602 0.91 PLA2G2A (0.50) PLA2G2A
SCHEMBL9284533 0.85 — —
SCHEMBL9281256 0.85 — —
SCHEMBL9221172 0.84 — —
SCHEMBL3266907 0.84 PLA2G2A (0.39) PLA2G2A
SCHEMBL3266909 0.84 PLA2G2A (0.39) PLA2G2A
SCHEMBL2023186 0.81 — —
SCHEMBL202015 0.81 — —
SCHEMBL457832 0.81 — —
SCHEMBL202012 0.81 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7868174-B2 Form of a benzenesulfonamide derivative PLIVA-ISTRAZIVANJE I RAZVOJ D.O.O. (HR) 2011-01-11 — — US disclosed
US-7868174-B2 Form of a benzenesulfonamide derivative PLIVA-ISTRAZIVANJE I RAZVOJ D.O.O. (HR) 2011-01-11 — — US disclosed
US-20080009629-A1 Novel Form of a Benzenesulfonamide Derivative PLIVA-ISTRAZIVANJE I RAZVOJ D.O.O. (HR) 2008-01-10 — — US disclosed
US-20080009629-A1 Novel Form of a Benzenesulfonamide Derivative PLIVA-ISTRAZIVANJE I RAZVOJ D.O.O. (HR) 2008-01-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080009629-A1 Novel Form of a Benzenesulfonamide Derivative ADH1A, ADH5, ADH1C PLA2G2A 3553/4885LTB4R 3924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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