Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 2/20 | 0.54 |
| ▸ | CCND1 | P24385 | 2/20 | 0.54 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20232146 | 0.96 | AHR (0.59) | CDK4CCND1AHRJAK2HSD17B10 | |
| SCHEMBL17154708 | 0.96 | CDK4 (0.57) | CDK4CCND1AHRJAK2HSD17B10 | |
| SCHEMBL30300831 | 0.96 | CDK4 (0.57) | CDK4CCND1AHRJAK2HSD17B10 | |
| SCHEMBL3365890 | 0.96 | CDK4 (0.57) | CDK4CCND1AHRJAK2HSD17B10 | |
| SCHEMBL12001022 | 0.96 | CDK4 (0.57) | CDK4CCND1AHRJAK2HSD17B10 | |
| SCHEMBL19041639 | 0.96 | CDK4 (0.57) | CDK4CCND1AHRJAK2HSD17B10 | |
| SCHEMBL149685 | 0.96 | CDK4 (0.57) | CDK4CCND1AHRJAK2HSD17B10 | |
| SCHEMBL29386403 | 0.96 | CDK4 (0.57) | CDK4CCND1AHRJAK2HSD17B10 | |
| SCHEMBL20233957 | 0.94 | AHR (0.61) | CDK4CCND1AHRJAK2HSD17B10 | |
| SCHEMBL20234009 | 0.94 | AHR (0.61) | CDK4CCND1AHRJAK2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3548481-B1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-08-23 | — | — | EP | disclosed |
| US-11329233-B2 | Heterocyclic compounds for use in electronic devices | MERCK PATENT GMBH (DE) | 2022-05-10 | — | — | US | disclosed |
| US-20190296250-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-09-26 | — | — | US | disclosed |
| WO-2018100029-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190296250-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | NQO1, DDT, ETV6 | CDK4 1313/4885CCND1 1962/4885AHR 75/4885 |
| US-11329233-B2 | Heterocyclic compounds for use in electronic devices | NQO1, DDT, ETV6 | CDK4 1313/4885CCND1 1962/4885AHR 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.