Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NPY1R | P25929 | 1/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | BRD4 | O60885 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | QPCT | Q16769 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13187054 | 0.75 | MEN1 (1.00) | L3MBTL1MEN1KMT2AALDH1A1GAA | |
| SCHEMBL20232997 | 0.75 | NPBWR1 (0.53) | L3MBTL1ALDH1A1CYP11B1CYP11B2LMNA | |
| SCHEMBL20233110 | 0.74 | KAT6A (0.52) | ALDH1A1GAANPY1RHTT | |
| SCHEMBL15579167 | 0.74 | KCNH2 (0.72) | L3MBTL1MEN1KMT2AALDH1A1GAA | |
| SCHEMBL23123003 | 0.74 | L3MBTL1 (0.61) | L3MBTL1MEN1KMT2AALDH1A1GAA | |
| SCHEMBL30138392 | 0.73 | HTT (0.72) | ALDH1A1CYP11B1CYP11B2LMNABRD4 | |
| SCHEMBL12771538 | 0.73 | HTT (0.72) | ALDH1A1CYP11B1CYP11B2LMNABRD4 | |
| SCHEMBL13186730 | 0.73 | MEN1 (0.77) | L3MBTL1MEN1KMT2AALDH1A1GAA | |
| SCHEMBL13560172 | 0.72 | MEN1 (0.69) | L3MBTL1MEN1KMT2AALDH1A1GAA | |
| SCHEMBL13187201 | 0.72 | MEN1 (0.69) | L3MBTL1MEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018102419-A1 | COMPOUNDS CONTAINING A SULFONIC GROUP AS KAT INHIBITORS | Epizyme, Inc. (US) | 2018-06-07 | — | — | WO | disclosed |