Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 11/20 | 0.48 |
| ▸ | LIPG | Q9Y5X9 | 11/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20180874 | 0.94 | LIPG (0.54) | LPLLIPGPRMT5WDR77F11 | |
| SCHEMBL15219034 | 0.94 | LIPG (0.54) | LPLLIPGPRMT5WDR77F11 | |
| SCHEMBL21944334 | 0.94 | LIPG (0.54) | LPLLIPGPRMT5WDR77F11 | |
| SCHEMBL24665490 | 0.88 | LIPG (0.44) | LPLLIPGPRMT5WDR77PDK2 | |
| SCHEMBL5095697 | 0.88 | LPL (0.48) | LPLLIPGPRMT5WDR77PDK2 | |
| SCHEMBL1999143 | 0.88 | LPL (0.48) | LPLLIPGPRMT5WDR77PDK2 | |
| SCHEMBL29950749 | 0.88 | LPL (0.48) | LPLLIPGPRMT5WDR77PDK2 | |
| SCHEMBL20233453 | 0.87 | LIPG (0.50) | LPLLIPGF11 | |
| SCHEMBL13429530 | 0.87 | LPL (0.47) | LPLLIPGF11 | |
| SCHEMBL19391924 | 0.87 | LIPG (0.47) | LPLLIPGPRMT5WDR77PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190296242-A1 | POLYMERS WITH ASYMMETRIC REPEATING UNITS | MERCK PATENT GMBH (DE) | 2019-09-26 | — | — | US | disclosed |
| WO-2018099847-A1 | POLYMERS WITH ASYMMETRIC REPEATING UNITS | MERCK PATENT GMBH (DE) | 2018-06-07 | — | — | WO | disclosed |