Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
| ▸ | FPR1 | P21462 | 2/20 | 0.46 |
| ▸ | FPR2 | P25090 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.44 |
| ▸ | ACACB | O00763 | 2/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20236407 | 1.00 | NPY5R (0.50) | NPY5RFPR1FPR2MCHR1NOTUM | |
| SCHEMBL24680813 | 0.89 | NOTUM (0.47) | NPY5RFPR1FPR2MCHR1NOTUM | |
| SCHEMBL29914613 | 0.89 | NOTUM (0.47) | NPY5RFPR1FPR2MCHR1NOTUM | |
| SCHEMBL1750257 | 0.83 | MCHR1 (0.42) | FPR1FPR2MCHR1NOTUMHRH4 | |
| SCHEMBL24681150 | 0.82 | MCHR1 (0.59) | NPY5RMCHR1NOTUMHRH4 | |
| SCHEMBL24681112 | 0.81 | FPR1 (0.43) | FPR1FPR2MCHR1NTRK1 | |
| SCHEMBL4263614 | 0.80 | FPR1 (0.44) | NPY5RFPR1FPR2MCHR1NOTUM | |
| SCHEMBL31084534 | 0.80 | FPR1 (0.44) | NPY5RFPR1FPR2MCHR1NOTUM | |
| SCHEMBL4259168 | 0.80 | FPR1 (0.44) | NPY5RFPR1FPR2MCHR1NOTUM | |
| SCHEMBL31322011 | 0.80 | HTR2B (0.44) | FPR1FPR2MCHR1NOTUMHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331864-A2 | 1,3,4-OXADIAZOLE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2018-06-13 | — | — | EP | disclosed |