SCHEMBL20237231

SCHEMBL20237231

COc1c(O)cccc1CCCO

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 3/20 0.44
SIGMAR1 Q99720 3/20 0.44
DRD1 P21728 2/20 0.44
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
ALOX5 P09917 1/20 0.42
PTGS2 P35354 1/20 0.42
MPO P05164 1/20 0.41
IAPP P10997 2/20 0.39
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
ALOX12 P18054 1/20 0.38
MAPK1 P28482 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27829507 0.89 DRD3 (0.46) DRD3SIGMAR1DRD1CA1CA2
SCHEMBL3362906 0.86 ALOX5 (0.54) DRD3SIGMAR1DRD1CA1CA2
SCHEMBL30056497 0.86 ALOX5 (0.54) DRD3SIGMAR1DRD1CA1CA2
SCHEMBL11218181 0.84 DRD3 (0.43) DRD3SIGMAR1DRD1CA1CA2
SCHEMBL25297854 0.84 TNKS2 (0.39) CA2TNKS2
SCHEMBL28328703 0.83 ALOX5 (0.59) ALOX5PTGS2KDM4ETP53CYP3A4
SCHEMBL27981225 0.83 ALOX5 (0.59) ALOX5PTGS2KDM4ETP53CYP3A4
SCHEMBL15228953 0.83 ALOX5 (0.59) ALOX5PTGS2KDM4ETP53CYP3A4
SCHEMBL985240 0.82 ALDH1A1 (0.51) CA1CA2ALOX5PTGS2KDM4E
SCHEMBL23964582 0.82 PTGER4 (0.43) CA1CA2ALOX5PTGS2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3331855-A1 NEW ANIONIC SURFACTANTS AND DETERGENTS COMPRISING THEM Henkel AG & Co. KGaA (DE) 2018-06-13 EP disclosed