Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 6/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9447682 | 0.79 | MIF (0.48) | MIFMEN1KMT2ADUSP3PTPN11 | |
| SCHEMBL9694765 | 0.78 | ALOX5 (0.42) | ALOX5PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL17156089 | 0.78 | MIF (0.49) | MIFMEN1KMT2ADUSP3PTPN11 | |
| SCHEMBL17156172 | 0.76 | MIF (0.46) | MIFMEN1KMT2ADUSP3PTPN11 | |
| SCHEMBL18418411 | 0.74 | MIF (0.58) | MIFMEN1KMT2ADUSP3PTPN11 | |
| SCHEMBL12376844 | 0.73 | MIF (0.55) | MIFMEN1KMT2APOLBMAPT | |
| SCHEMBL18421326 | 0.72 | MIF (0.50) | MIFMEN1KMT2APOLBMAPT | |
| SCHEMBL18418413 | 0.70 | MIF (0.69) | MIFMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL17156221 | 0.70 | MIF (0.68) | MIFPOLBMAPTALDH1A1MAPK1 | |
| SCHEMBL9694937 | 0.70 | ALOX5 (0.37) | ALOX5PTGS1PTGS2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2929882-B1 | MIF inhibitors | MIFCARE (FR) | 2018-06-13 | — | — | EP | claimed |