Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9694937 | 0.91 | ALOX5 (0.37) | ALOX5PTGS1PTGS2L3MBTL1KDM4E | |
| SCHEMBL9694960 | 0.86 | L3MBTL1 (0.42) | L3MBTL1KDM4EPKMLMNATSHR | |
| SCHEMBL9694913 | 0.79 | L3MBTL1 (0.39) | L3MBTL1KDM4EPKMLMNATSHR | |
| SCHEMBL9694390 | 0.79 | F2R (0.39) | L3MBTL1KDM4EPKMLMNATSHR | |
| SCHEMBL20237367 | 0.78 | MIF (0.46) | ALOX5PTGS1PTGS2HTTGAA | |
| SCHEMBL9694565 | 0.78 | ALDH1A1 (0.39) | L3MBTL1KDM4EPKMTSHRGAA | |
| SCHEMBL9694885 | 0.76 | ALDH1A1 (0.39) | L3MBTL1KDM4EPKMLMNATSHR | |
| SCHEMBL9694539 | 0.74 | L3MBTL1 (0.46) | L3MBTL1KDM4EPKMLMNATSHR | |
| SCHEMBL9694360 | 0.73 | F2R (0.43) | L3MBTL1KDM4EPKMLMNATSHR | |
| SCHEMBL9694402 | 0.73 | L3MBTL1 (0.40) | L3MBTL1KDM4EPKMLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10160732-B2 | MIF inhibitors | MIFCARE (FR) | 2018-12-25 | — | — | US | claimed |
| EP-2929882-B1 | MIF inhibitors | MIFCARE (FR) | 2018-06-13 | — | — | EP | claimed |
| US-20170029387-A1 | MIF INHIBITORS | APAXEN (BE) | 2017-02-02 | — | — | US | claimed |
| WO-2015155358-A1 | MIF INHIBITORS | MIFCARE (FR) | 2015-10-15 | — | — | WO | claimed |
| EP-2929882-A1 | MIF inhibitors | Mifcare (FR) | 2015-10-14 | — | — | EP | claimed |
| US-10160732-B2 | MIF inhibitors | MIFCARE (FR) | 2018-12-25 | — | — | US | disclosed |
| EP-2929882-B1 | MIF inhibitors | MIFCARE (FR) | 2018-06-13 | — | — | EP | disclosed |
| US-20170029387-A1 | MIF INHIBITORS | APAXEN (BE) | 2017-02-02 | — | — | US | disclosed |
| WO-2015155358-A1 | MIF INHIBITORS | MIFCARE (FR) | 2015-10-15 | — | — | WO | disclosed |
| EP-2929882-A1 | MIF inhibitors | Mifcare (FR) | 2015-10-14 | — | — | EP | disclosed |
| EP-1468331-B1 | POLYMERIC MATERIAL CONTAINING A LATENT ACID | BASF SE (DE) | 2012-10-03 | — | — | EP | disclosed |
| US-8003297-B2 | Polymeric material, containing a latent acid | BASF SE (DE) | 2011-08-23 | — | — | US | disclosed |
| US-20070054220-A1 | Polymeric material, containing a latent acid | HENEGHAN MICHAEL | 2007-03-08 | — | — | US | disclosed |
| US-20070054220-A1 | Polymeric material, containing a latent acid | HENEGHAN MICHAEL | 2007-03-08 | — | — | US | disclosed |
| US-5169950-A | Reacting a 2-mercaptobenzothiazole, acarbonyl and a phenol; basic catalyst; polar solvent | CIBA-GEIGY CORPORATION (US) | 1992-12-08 | — | — | US | disclosed |
| US-5097039-A | Coating, lubricants | CIBA-GEIGY CORPORATION (US) | 1992-03-17 | — | — | US | disclosed |
| US-5069805-A | OIL ADDITIVES | CIBA-GEIGY CORPORATION (US) | 1991-12-03 | — | — | US | disclosed |
| EP-0259254-B1 | PHENOLIC BENZOTHIAZOLE DERIVATIVES AND THEIR USE AS CORROSION INHIBITORS | CIBA-GEIGY AG (CH) | 1991-04-17 | — | — | EP | disclosed |
| US-4894091-A | PROTECTIVE COATINGS, PHOTOSTABILIZERS, HEAT RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1990-01-16 | — | — | US | disclosed |
| EP-0259254-A1 | Phenolic benzothiazole derivatives and their use as corrosion inhibitors | CIBA-GEIGY AG (CH) | 1988-03-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10160732-B2 | MIF inhibitors | MIF, MSR1, MMP12 | ALOX5 762/4885PTGS1 33/4885PTGS2 63/4885 |
| US-20170029387-A1 | MIF INHIBITORS | MIF, MSR1, MMP12 | ALOX5 762/4885PTGS1 33/4885PTGS2 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.