SCHEMBL202386

SCHEMBL202386

C=C(C)C(=O)Nc1ccc(C#N)c(C(F)(F)F)c1

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AR P10275 6/20 0.52
TAS2R14 Q9NYV8 1/20 0.51
CYP2C19 P33261 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29415541 1.00 AR (0.52) ARTAS2R14CYP2C19
SCHEMBL5664793 0.89 AR (0.55) ARTAS2R14
SCHEMBL202266 0.86 AR (0.52) ARTAS2R14CYP2C19
SCHEMBL13167546 0.86 AR (0.52) ARTAS2R14
SCHEMBL14289402 0.86 AR (0.59) ARCYP2C19
SCHEMBL21155661 0.86 AR (0.55) AR
SCHEMBL202061 0.86 AR (0.52) ARCYP2C19
SCHEMBL10811597 0.85 AR (0.51) ARTAS2R14
SCHEMBL10811606 0.85 AR (0.51) ARTAS2R14
SCHEMBL26365675 0.84 AR (0.53) ARTAS2R14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 360 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117863696-B MLCC release film base film and preparation method thereof 蔚芮德新材料科技江苏有限公司 2024-07-05 CN claimed
CN-118281169-A High-cycle dry electrode film and preparation method thereof 苏州市新广益电子股份有限公司 2024-07-02 CN claimed
CN-118240452-A Easy-to-clean coating and preparation method and application thereof 北京中路高科交通咨询有限公司 2024-06-25 CN claimed
CN-118223153-A Antistatic artificial lawn and preparation method thereof 扬州市畅优草坪地毯有限公司 2024-06-21 CN claimed
CN-118108417-A Coating liquid for photovoltaic coated glass and 1.6mm coating process 无锡海达光能股份有限公司 2024-05-31 CN claimed
CN-118065052-A Light, thin and high-strength non-woven fabric and preparation method thereof 扬州丽铂环保材料有限公司 2024-05-24 CN claimed
CN-118045490-A Composite ultrafiltration membrane and preparation method thereof 上海乐纯生物技术股份有限公司 2024-05-17 CN claimed
CN-117945962-A Synthesis method of bicalutamide 中国人民大学 2024-04-30 CN claimed
CN-117936826-A Polyelectrolyte diaphragm for fuel cell and preparation method thereof 扬州雄鸡电池有限公司 2024-04-26 CN claimed
CN-117863696-A MLCC release film base film and preparation method thereof 蔚芮德新材料科技江苏有限公司 2024-04-12 CN claimed
CN-112250979-A Environment-friendly tire rubber material and preparation method thereof 王玉龙 2021-01-22 CN claimed
CN-111924419-A Wear-resisting belt of bucket wheel belt feeder ageing resistance 湖南长重机器股份有限公司 2020-11-13 CN claimed
CN-111234380-A Environment-friendly automotive interior composite material and preparation method thereof 刘超 2020-06-05 CN claimed
CN-111087367-A Synthesis method of N- (4 cyano-3- (trifluoromethyl) phenyl) -2-methyl epoxy propylene-2-amide 苏州永健生物医药有限公司 2020-05-01 CN claimed
CN-111038056-A Environment-friendly tent material and preparation method thereof 郭涛 2020-04-21 CN claimed
CN-106831509-B A kind of synthetic method of Bicalutamide 西北师范大学 2018-05-18 CN claimed
US-8288579-B2 Method for producing N-methacryloyl-4-cyano-3-trifluoromethylaniline SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-16 US claimed
US-20100249446-A1 METHOD FOR PRODUCING N-METHACRYLOYL-4-CYANO-3-TRIFLUOROMETHYLANILINE SUMITOMO CHEMICAL COMPANY, LIMITED 2010-09-30 US claimed
EP-2204362-A1 METHOD FOR PRODUCING N-METHACRYLOYL-4-CYANO-3-TRIFLUOROMETHYLANILINE Sumitomo Chemical Company, Limited (JP) 2010-07-07 EP claimed
WO-2004039791-A1 A PROCESS FOR THE PRODUCTION OF N-(4-CYANO-3-TRIFLUOROMETHYLPHENYL)-2,3-EPOXY-2-METHYLPROPANAMIDE INSTYTUT FARMACEUTYCZNY (PL) 2004-05-13 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249446-A1 METHOD FOR PRODUCING N-METHACRYLOYL-4-CYANO-3-TRIFLUOROMETHYLANILINE ACR, ACMSD, NANS AR 3782/4885TAS2R14 1597/4885CYP2C19 2767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.