Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 11/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 2/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2710062 | 1.00 | MCL1 (0.46) | MCL1CYP2D6CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4421755 | 1.00 | MCL1 (0.46) | MCL1CYP2D6CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7407670 | 1.00 | MCL1 (0.46) | MCL1CYP2D6CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL14143865 | 1.00 | MCL1 (0.46) | MCL1CYP2D6CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6847660 | 1.00 | MCL1 (0.46) | MCL1CYP2D6CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL13481726 | 0.91 | MCL1 (0.44) | MCL1CYP2D6CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1890321 | 0.91 | MCL1 (0.44) | MCL1CYP2D6CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL3187965 | 0.91 | MCL1 (0.44) | MCL1CYP2D6CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30148070 | 0.91 | MCL1 (0.44) | MCL1CYP2D6CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11300131 | 0.91 | MCL1 (0.46) | MCL1HSD11B1UCHL1NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240190930-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | UNIV NEW YORK (US) | 2024-06-13 | — | — | US | disclosed |
| US-11891422-B2 | NEMO coiled coil mimics and methods of using same | NEW YORK UNIVERSITY (US) | 2024-02-06 | — | — | US | disclosed |
| US-20210277059-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | UNIV NEW YORK (US) | 2021-09-09 | — | — | US | disclosed |
| US-10851133-B2 | Stabilized minimal coiled-coil mimetics | NEW YORK UNIVERSITY (US) | 2020-12-01 | — | — | US | disclosed |
| US-20200190155-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | NEW YORK UNIVERSITY | 2020-06-18 | — | — | US | disclosed |
| US-20180162907-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | NEW YORK UNIVERSITY | 2018-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10851133-B2 | Stabilized minimal coiled-coil mimetics | COIL, CALCOCO2, CRYZ | MCL1 3079/4885CYP2D6 4879/4885CYP1A2 4881/4885 |
| US-20210277059-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | COIL, CALCOCO2, CRYZ | MCL1 3079/4885CYP2D6 4879/4885CYP1A2 4881/4885 |
| US-11891422-B2 | NEMO coiled coil mimics and methods of using same | COIL, CALCOCO2, NCAPH | MCL1 2920/4885CYP2D6 3309/4885CYP1A2 2802/4885 |
| US-20200190155-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | COIL, CALCOCO2, NCAPH | MCL1 2920/4885CYP2D6 3309/4885CYP1A2 2802/4885 |
| US-20180162907-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | COIL, CALCOCO2, CRYZ | MCL1 3079/4885CYP2D6 4879/4885CYP1A2 4881/4885 |
| US-20240190930-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | COIL, CALCOCO2, NCAPH | MCL1 2745/4885CYP2D6 3195/4885CYP1A2 2591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.