SCHEMBL2023914

SCHEMBL2023914

C=C(C)c1ccccc1[C](C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
NPC1 O15118 1/20 0.36
CLCN2 P51788 1/20 0.34
ALDH1A1 P00352 4/20 0.33
ALOX15 P16050 2/20 0.33
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
PAX8 Q06710 1/20 0.32
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA4 P22748 2/20 0.32
CA7 P43166 2/20 0.32
CA9 Q16790 2/20 0.32
HPGD P15428 2/20 0.31
KDM4E B2RXH2 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29434165 0.91 MEN1 (0.40) MEN1KMT2ANPC1CLCN2ALDH1A1
SCHEMBL107161 0.91 MEN1 (0.40) MEN1KMT2ANPC1CLCN2ALDH1A1
Hydrogen Sulfide SCHEMBL26644763 0.88 MEN1 (0.39) MEN1KMT2ANPC1CLCN2ALDH1A1
Hydrogen Peroxide SCHEMBL28416110 0.88 ALDH1A1 (0.43) MEN1KMT2ANPC1CLCN2ALDH1A1
SCHEMBL6003981 0.88 MEN1 (0.39) MEN1KMT2ANPC1CLCN2ALDH1A1
SCHEMBL30622076 0.88 MEN1 (0.39) MEN1KMT2ANPC1CLCN2ALDH1A1
Lithium SCHEMBL6003985 0.88 MEN1 (0.39) MEN1KMT2ANPC1CLCN2ALDH1A1
SCHEMBL4426071 0.88 MEN1 (0.39) MEN1KMT2ANPC1CLCN2ALDH1A1
SCHEMBL1548711 0.85 NPC1 (0.43) MEN1KMT2ANPC1ALDH1A1ALOX15
SCHEMBL23844114 0.81 ALDH1A1 (0.38) MEN1KMT2ANPC1CLCN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9061089-B2 Biocompatible, biodegradable polyurethane materials with controlled hydrophobic to hydrophilic ratio DePuy Synthes Products, Inc. (US) 2015-06-23 US claimed
EP-1771490-A1 BIOCOMPATIBLE, BIODEGRADABLE POLYURETHANE MATERIALS WITH CONTROLLED HYDROPHOBIC TO HYDROPHILIC RATIO Synthes GmbH (CH) 2007-04-11 EP claimed
WO-2006010278-A1 BIOCOMPATIBLE, BIODEGRADABLE POLYURETHANE MATERIALS WITH CONTROLLED HYDROPHOBIC TO HYDROPHILIC RATIO SYNTHES GMBH (CH) 2006-02-02 WO claimed
CN-1577129-A Gel organosol including amphipathic copolymeric binder having crosslinking functionality and liquid toners for electrophotographic applications SAMSUNG ELECTRONICS CO LTD (KR) 2005-02-09 CN claimed
EP-0385457-B1 High surface hardness transparent resin and polymerizable monomer MITSUI TOATSU CHEMICALS (JP) 1994-06-01 EP claimed
US-5250723-A Copolymerizable monomer containing carbamate or thiocarbamate, ether and isopropenylphenyl groups; protective coatings; optical lenses; hardness; scratch, heat and chemical resistances MITSUI TOATSU CHEMICALS, INC. (JP) 1993-10-05 US claimed
US-5198480-A Reducing styrene emission during curing, polyethers, polyethersiloxane copolymers THE STANDARD OIL COMPANY (US) 1993-03-30 US claimed
US-5145927-A Protective cover for display devices or optical lenses MITSUI TOATSU CHEMICALS, INC. (JP) 1992-09-08 US claimed
EP-0385457-A2 High surface hardness transparent resin and polymerizable monomer MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-09-05 EP claimed
EP-0234353-A1 Process for the production of tetramethyl xylylene diisocyanates AMERICAN CYANAMID COMPANY (US) 1987-09-02 EP claimed
EP-3065944-B1 MODIFICATION OF POLYAMIDES ARKEMA INC (US) 2022-01-19 EP disclosed
US-10787604-B2 Colored organic peroxide compositions and methods for breaking fluids ARKEMA INC. (US) 2020-09-29 US disclosed
US-10358559-B2 Colored organic peroxide compositions ARKEMA INC. (US) 2019-07-23 US disclosed
US-10294414-B2 Compositions and methods for breaking hydraulic fracturing fluids ARKEMA INC. (US) 2019-05-21 US disclosed
US-10138413-B2 Promoters for peroxides in aqueous treatment fluids ARKEMA INC. (US) 2018-11-27 US disclosed
US-5393607-A Glazing materials; hardness, impact strength, scratch resistance MITSUI TOATSU CHEMICLAS, INC. (JP) 1995-02-28 US disclosed
EP-0551867-A1 Laminated transparent plastic material and polymerizable monomer MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-07-21 EP disclosed
US-5198480-A Reducing styrene emission during curing, polyethers, polyethersiloxane copolymers THE STANDARD OIL COMPANY (US) 1993-03-30 US disclosed
US-5145927-A Protective cover for display devices or optical lenses MITSUI TOATSU CHEMICALS, INC. (JP) 1992-09-08 US disclosed
EP-0234353-A1 Process for the production of tetramethyl xylylene diisocyanates AMERICAN CYANAMID COMPANY (US) 1987-09-02 EP disclosed