Lithium

Lithium

SCHEMBL6003985

C=C(C)c1ccccc1C(=C)C.[Li].[Li]

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 5/20 0.36
ALOX15 P16050 2/20 0.36
CLCN2 P51788 1/20 0.36
ADRA2A P08913 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA4 P22748 2/20 0.34
CA7 P43166 2/20 0.34
CA9 Q16790 2/20 0.34
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
PAX8 Q06710 1/20 0.34
TSHR P16473 3/20 0.33
HPGD P15428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL107161 0.97 MEN1 (0.40) MEN1KMT2ANPC1ALDH1A1ALOX15
SCHEMBL29434165 0.97 MEN1 (0.40) MEN1KMT2ANPC1ALDH1A1ALOX15
SCHEMBL6003981 0.94 MEN1 (0.39) MEN1KMT2ANPC1ALDH1A1ALOX15
SCHEMBL4426071 0.94 MEN1 (0.39) MEN1KMT2ANPC1ALDH1A1ALOX15
SCHEMBL30622076 0.94 MEN1 (0.39) MEN1KMT2ANPC1ALDH1A1ALOX15
Hydrogen Sulfide SCHEMBL26644763 0.94 MEN1 (0.39) MEN1KMT2ANPC1ALDH1A1ALOX15
Hydrogen Peroxide SCHEMBL28416110 0.94 ALDH1A1 (0.43) MEN1KMT2ANPC1ALDH1A1ALOX15
SCHEMBL2023914 0.88 MEN1 (0.36) MEN1KMT2ANPC1ALDH1A1ALOX15
SCHEMBL23844114 0.86 ALDH1A1 (0.38) MEN1KMT2ANPC1ALDH1A1ALOX15
SCHEMBL8297060 0.84 SMN1; SMN2 (0.42) MEN1KMT2AALDH1A1ALOX15CLCN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4894409-A BLEND OR AMINO GROUP CONTAINING DIENE POLYMER AND SILICA FILLER NONCRACKING, WEAR RESISTANCE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1990-01-16 US claimed
EP-3555144-B1 METHOD FOR SYNTHESIS OF MODIFIED DIENE POLYMERS BY GROUPS DERIVED FROM ANTHRACEN, PRODUCT OBTAINED FROM SAID METHOD AND COMPOSITION CONTAINING SAME MICHELIN & CIE (FR) 2023-06-21 EP disclosed
EP-1339783-B1 ELASTOMERIC COMPOSITION COMPRISING A FUNCTIONALIZED ELASTOMER POLIMERI EUROPA SPA (IT) 2006-05-03 EP disclosed
US-7015277-B2 Elastomeric composition comprising a functionalized elastomer POLIMERI EUROPA S.P.A. (IT) 2006-03-21 US disclosed
US-20040152822-A1 Elastomeric composition comprising a functionalized elastomer POLIMERI EUROPA S.P.A. (IT) 2004-08-05 US disclosed
US-20040019144-A1 Elastomeric composition useful for tire treads ENICHEM ELASTOMERI S.R.L. (IT) 2004-01-29 US disclosed
EP-1339783-A1 ELASTOMERIC COMPOSITION COMPRISING A FUNCTIONALIZED ELASTOMER Polimeri Europa S.p.A. (IT) 2003-09-03 EP disclosed
US-6613858-B1 Block copolymer having narrow molecular weight distribution and excellent symmetrical property or a telechelic polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2003-09-02 US disclosed
US-20030120007-A1 ELASTOMERIC COMPOSITION USEFUL AS TIRE TREADS BORTOLOTTI MICHELE (IT) 2003-06-26 US disclosed
US-6569942-B2 Pneumatic tires THE GOODYEAR TIRE & RUBBER COMPANY 2003-05-27 US disclosed
EP-0447066-B2 Pneumatic tyres BRIDGESTONE CORP (JP) 2000-08-16 EP disclosed
EP-0824133-A1 Silica-filled rubber compositions and the processing thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-02-18 EP disclosed
US-5708053-A Silica-filled rubber compositions and the processing thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-01-13 US disclosed
EP-0763564-A2 elastomeric composition useful for tyre treads ENICHEM ELASTOMERI S.r.l. (IT) 1997-03-19 EP disclosed
US-5496883-A COMPRISING TREAD RUBBER OF POLYBUTADIENE POLYMER OR COPOLYMER CONTAINING SILICA AND MODIFIED WITH SILANE COUPLING AGENT; COUPLING AGENT; WET SKID RESISTANCE, LOW ROLLLING RESISTANCE BRIDGESTONE CORPORATION (JP) 1996-03-05 US disclosed
EP-0489921-B1 REDUCED HEAT-BUILDUP RUBBER COMPOSITION BRIDGESTONE CORP (JP) 1995-09-13 EP disclosed
US-5409969-A Comprising silica filler, carbon black, silane coupler, living polymer of butadiene-styrene BRIDGESTONE CORPORATION (JP) 1995-04-25 US disclosed
EP-0489921-A1 REDUCED HEAT-BUILDUP RUBBER COMPOSITION Bridgestone Corporation (JP) 1992-06-17 EP disclosed
EP-0447066-A1 Pneumatic tyres Bridgestone Corporation (JP) 1991-09-18 EP disclosed
US-4894409-A BLEND OR AMINO GROUP CONTAINING DIENE POLYMER AND SILICA FILLER NONCRACKING, WEAR RESISTANCE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1990-01-16 US disclosed