SCHEMBL20239471

SCHEMBL20239471

COC(=O)C(C)(C)OCc1cc(-c2cc(Br)cs2)n(Cc2ccccc2Cl)n1

nearest known ligand 0.70

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ SLC16A3 O15427 20/20 0.70
▸ SLC16A1 P53985 19/20 0.70
▸ MCTS1 Q9ULC4 12/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29819644 1.00 SLC16A3 (0.70) SLC16A3SLC16A1MCTS1
SCHEMBL29487685 0.92 SLC16A3 (0.66) SLC16A3SLC16A1MCTS1
SCHEMBL20239564 0.91 SLC16A3 (0.80) SLC16A3SLC16A1MCTS1
SCHEMBL20239622 0.86 SLC16A3 (0.85) SLC16A3SLC16A1MCTS1
SCHEMBL31130177 0.86 SLC16A3 (0.85) SLC16A3SLC16A1MCTS1
SCHEMBL18307411 0.84 SLC16A3 (0.83) SLC16A3SLC16A1MCTS1
SCHEMBL31130146 0.83 SLC16A3 (0.84) SLC16A3SLC16A1MCTS1
SCHEMBL18307500 0.82 SLC16A3 (0.87) SLC16A3SLC16A1MCTS1
SCHEMBL18300861 0.82 SLC16A3 (1.00) SLC16A3SLC16A1MCTS1
SCHEMBL29487692 0.82 SLC16A3 (1.00) SLC16A3SLC16A1MCTS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260055062-A1 HETEROCYCLIC INHIBITORS OF MCT4 Vettore, LLC 2026-02-26 — — US disclosed
US-12492171-B2 Heterocyclic inhibitors of MCT4 Vettore, LLC (US) 2025-12-09 — — US disclosed
EP-4442318-A2 HETEROCYCLIC INHIBITORS OF MCT4 Vettore, LLC (US) 2024-10-09 — — EP disclosed
CN-110114351-B Heterocyclic inhibitors of MCT4 维托尔股份有限公司 2022-09-20 — — CN disclosed
US-20220251047-A1 HETEROCYCLIC INHIBITORS OF MCT4 Vettore, LLC 2022-08-11 — — US disclosed
US-11292767-B2 Heterocyclic inhibitors of MCT4 Vettore, LLC (US) 2022-04-05 — — US disclosed
EP-3551625-A1 HETEROCYCLIC INHIBITORS OF MCT4 Vettore, LLC (US) 2019-10-16 — — EP disclosed
US-20190112275-A1 HETEROCYCLIC INHIBITORS OF MCT4 Vettore, LLC 2019-04-18 — — US disclosed
WO-2018111904-A1 HETEROCYCLIC INHIBITORS OF MCT4 Vettore, LLC (US) 2018-06-21 — — WO disclosed
US-20180162822-A1 HETEROCYCLIC INHIBITORS OF MCT4 Vettore, LLC 2018-06-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12492171-B2 Heterocyclic inhibitors of MCT4 SLC16A3, SLC16A1, MCTS1 SLC16A3 1/4885SLC16A1 2/4885MCTS1 3/4885
US-11292767-B2 Heterocyclic inhibitors of MCT4 SLC16A3, SLC16A1, MCTS1 SLC16A3 1/4885SLC16A1 2/4885MCTS1 3/4885
US-20190112275-A1 HETEROCYCLIC INHIBITORS OF MCT4 SLC16A3, SLC16A1, MCTS1 SLC16A3 1/4885SLC16A1 2/4885MCTS1 3/4885
US-20220251047-A1 HETEROCYCLIC INHIBITORS OF MCT4 SLC16A3, SLC16A1, MCTS1 SLC16A3 1/4885SLC16A1 2/4885MCTS1 3/4885
US-20180162822-A1 HETEROCYCLIC INHIBITORS OF MCT4 SLC16A3, SLC16A1, MCTS1 SLC16A3 1/4885SLC16A1 2/4885MCTS1 3/4885
US-20260055062-A1 HETEROCYCLIC INHIBITORS OF MCT4 SLC16A1, SLC16A3, SLC16A7 SLC16A3 2/4885SLC16A1 1/4885MCTS1 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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