SCHEMBL202398

SCHEMBL202398

N#CCCNc1ccccc1CCO

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.36
HTT P42858 3/20 0.36
ALDH1A1 P00352 2/20 0.36
THRB P10828 1/20 0.35
KDM4E B2RXH2 3/20 0.35
TSHR P16473 3/20 0.35
MAPT P10636 2/20 0.35
HPGD P15428 2/20 0.35
HSD17B10 Q99714 2/20 0.35
GLA P06280 1/20 0.34
CA12 O43570 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
TRPV1 Q8NER1 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 2/20 0.31
DRD3 P35462 1/20 0.31
GUSB P08236 1/20 0.30
PARG Q86W56 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28195586 0.87 KDM4E (0.41) GAAHTTALDH1A1KDM4ETSHR
SCHEMBL3492989 0.82 KDM4E (0.47) GAAHTTALDH1A1KDM4ETSHR
SCHEMBL11248471 0.80 GAA (0.46) GAAHTTALDH1A1THRBKDM4E
SCHEMBL2229383 0.79 GAA (0.42) GAAHTTALDH1A1THRBMAPT
SCHEMBL9184322 0.76 MEN1 (0.43) ALDH1A1KDM4ETSHRMAPTHPGD
SCHEMBL9177752 0.76 ALDH1A1 (0.56) GAAHTTALDH1A1KDM4ETSHR
SCHEMBL10498975 0.75 MAPT (0.46) GAAHTTALDH1A1THRBKDM4E
SCHEMBL8283681 0.73 MEN1 (0.43) GAAHTTALDH1A1KDM4ETSHR
SCHEMBL932125 0.72 TDP1 (0.40) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL31310613 0.72 KDM4E (0.44) GAAALDH1A1KDM4ETSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2121324-B1 RADIATION-SENSITIVE COMPOSITIONS AND ELEMENTS WITH BASIC DEVELOPMENT ENHANCERS EASTMAN KODAK CO (US) 2014-06-04 EP claimed
US-20130008331-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2013-01-10 US claimed
WO-2011113693-A1 A LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2011-09-22 WO claimed
EP-2121324-A1 RADIATION-SENSITIVE COMPOSITIONS AND ELEMENTS WITH BASIC DEVELOPMENT ENHANCERS EASTMAN KODAK COMPANY (US) 2009-11-25 EP claimed
US-7544462-B2 Radiation-sensitive composition and elements with basic development enhancers EASTMAN KODAK COMPANY (US) 2009-06-09 US claimed
US-20080206678-A1 RADIATION-SENSITIVE COMPOSITIONS AND ELEMENTS WITH BASIC DEVELOPMENT ENHANCERS EASTMAN KODAK COMPANY 2008-08-28 US claimed
WO-2008103258-A1 RADIATION-SENSITIVE COMPOSITIONS AND ELEMENTS WITH BASIC DEVELOPMENT ENHANCERS EASTMAN KODAK COMPANY (US) 2008-08-28 WO claimed
EP-3429864-B1 METHOD AND APPARATUS FOR PROCESSING A LITHOGRAPHIC PRINTING PLATE ECO3 BV (BE) 2025-11-19 EP disclosed
US-20220288916-A1 Method for Processing a Lithographic Printing Plate AGFA OFFSET BE (BE) 2022-09-15 US disclosed
EP-4013621-A1 METHOD FOR PROCESSING A LITHOGRAPHIC PRINTING PLATE AGFA OFFSET BV (BE) 2022-06-22 EP disclosed
EP-3429852-B1 METHOD FOR PROCESSING A LITHOGRAPHIC PRINTING PLATE AGFA NV (BE) 2021-11-10 EP disclosed
EP-3429851-B1 METHOD FOR PROCESSING A LITHOGRAPHIC PRINTING PLATE AGFA NV (BE) 2021-08-18 EP disclosed
EP-3429848-B1 METHOD FOR PROCESSING A LITHOGRAPHIC PRINTING PLATE AGFA NV (BE) 2021-08-18 EP disclosed
WO-2009085093-A1 RADIATION-SENSITIVE ELEMENTS WITH DEVELOPABILITY-ENHANCING COMPOUNDS EASTMAN KODAK COMPANY (US) 2009-07-09 WO disclosed
US-20090162783-A1 RADIATION-SENSITIVE ELEMENTS WITH DEVELOPABILITY-ENHANCING COMPOUNDS BANK OF AMERICA, N.A., AS AGENT 2009-06-25 US disclosed
US-7544462-B2 Radiation-sensitive composition and elements with basic development enhancers EASTMAN KODAK COMPANY (US) 2009-06-09 US disclosed
WO-2008106010-A1 POSITIVE-WORKING RADIATION-SENSITIVE COMPOSITIONS AND ELEMENTS EASTMAN KODAK COMPANY (US) 2008-09-04 WO disclosed
US-20080206678-A1 RADIATION-SENSITIVE COMPOSITIONS AND ELEMENTS WITH BASIC DEVELOPMENT ENHANCERS EASTMAN KODAK COMPANY 2008-08-28 US disclosed
WO-2008103258-A1 RADIATION-SENSITIVE COMPOSITIONS AND ELEMENTS WITH BASIC DEVELOPMENT ENHANCERS EASTMAN KODAK COMPANY (US) 2008-08-28 WO disclosed
US-7399576-B1 To prepare imageable elements useful to make lithographic printing plates; coating quality and less surface defects; friction between the outermost imageable layer and overlying interleaf papers used in stacks of elements is optimized so that the stacks of plates are sliding during transportation EASTMAN KODAK COMPANY (US) 2008-07-15 US disclosed