Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31310613 | 0.88 | KDM4E (0.44) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL3492989 | 0.85 | KDM4E (0.47) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL9257331 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTTSHRLMNA | |
| SCHEMBL14027597 | 0.77 | IDO1 (0.44) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL9288793 | 0.77 | ADRB2 (0.37) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL9729179 | 0.77 | KDM4E (0.47) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL10523676 | 0.77 | KDM4E (0.47) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL202398 | 0.76 | GAA (0.36) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL9257742 | 0.76 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL8283681 | 0.76 | MEN1 (0.43) | ALDH1A1KDM4EMAPTGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664788-A1 | SUBSTITUTED ETHANOLAMINE ESTERS | Byk Nederland BV (NL) | 1995-08-02 | — | — | EP | disclosed |