Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | JAK3 | P52333 | 2/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20242505 | 0.89 | HTR6 (0.62) | HTR6MAPTMAPK1ALDH1A1KMT2A | |
| SCHEMBL21378916 | 0.88 | HTR6 (0.50) | HTR6MAPTMAPK1ALDH1A1KMT2A | |
| SCHEMBL20242252 | 0.88 | HTR6 (0.50) | HTR6MAPTMAPK1ALDH1A1KMT2A | |
| SCHEMBL20242670 | 0.87 | HTR6 (0.57) | HTR6MAPTMAPK1 | |
| SCHEMBL20242536 | 0.87 | HTR6 (0.49) | HTR6MAPTMAPK1ALDH1A1KMT2A | |
| SCHEMBL20242534 | 0.86 | HTR6 (0.48) | HTR6MAPTMAPK1ALDH1A1KMT2A | |
| SCHEMBL20241883 | 0.86 | HTR6 (0.48) | HTR6MAPTMAPK1ALDH1A1KMT2A | |
| SCHEMBL20242472 | 0.85 | HTR6 (0.47) | HTR6MAPTMAPK1ALDH1A1KMT2A | |
| SCHEMBL20242151 | 0.85 | ACHE (0.50) | HTR6MAPTMAPK1ALDH1A1KMT2A | |
| SCHEMBL20241570 | 0.85 | HTR6 (0.62) | HTR6MAPTMAPK1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11459308-B2 | Broad spectrum inhibitors of filoviruses | MICROBIOTIX, INC. (US) | 2022-10-04 | — | — | US | claimed |
| US-20190292165-A1 | BROAD SPECTRUM INHIBITORS OF FILOVIRUSES | MICROBIOTIX, INC. (US) | 2019-09-26 | — | — | US | claimed |
| US-11459308-B2 | Broad spectrum inhibitors of filoviruses | MICROBIOTIX, INC. (US) | 2022-10-04 | — | — | US | disclosed |
| EP-3548034-A1 | BROAD-SPECTRUM INHIBITORS OF FILOVIRUSES | Microbiotix, Inc. (US) | 2019-10-09 | — | — | EP | disclosed |
| US-20190292165-A1 | BROAD SPECTRUM INHIBITORS OF FILOVIRUSES | MICROBIOTIX, INC. (US) | 2019-09-26 | — | — | US | disclosed |
| WO-2018106667-A1 | BROAD-SPECTRUM INHIBITORS OF FILOVIRUSES | MICROBIOTIX, INC. (US) | 2018-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11459308-B2 | Broad spectrum inhibitors of filoviruses | NPC1L1, NPC1, GBA1 | HTR6 4498/4885MAPT 3677/4885MAPK1 3678/4885 |
| US-20190292165-A1 | BROAD SPECTRUM INHIBITORS OF FILOVIRUSES | NPC1L1, NPC1, GBA1 | HTR6 4498/4885MAPT 3677/4885MAPK1 3678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.