SCHEMBL20243189

SCHEMBL20243189

NC(CCCCB(O)O)(CCN1Cc2ccccc2C[C@H]1CO)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 19/20 0.69
ARG2 P78540 18/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL893947 1.00 ARG1 (0.69) ARG1ARG2
SCHEMBL10265968 1.00 ARG1 (0.69) ARG1ARG2
SCHEMBL30169896 1.00 ARG1 (0.69) ARG1ARG2
SCHEMBL893946 1.00 ARG1 (0.69) ARG1ARG2
Hydrochloric Acid SCHEMBL895559 0.99 ARG1 (0.68) ARG1ARG2
Hydrochloric Acid SCHEMBL895557 0.99 ARG1 (0.68) ARG1ARG2
SCHEMBL20683336 0.88 ARG1 (0.51) ARG1ARG2
SCHEMBL19055961 0.86 ARG1 (0.61) ARG1ARG2
SCHEMBL895121 0.84 ARG2 (0.63) ARG1ARG2
SCHEMBL30169798 0.84 ARG2 (0.63) ARG1ARG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9994594-B2 Inhibitors of arginase and their therapeutic applications MARS, INCORPORATED (US) 2018-06-12 US disclosed