Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 7/20 | 0.71 |
| ▸ | GRIN2A | Q12879 | 7/20 | 0.71 |
| ▸ | GRIN2D | O15399 | 6/20 | 0.71 |
| ▸ | GRIN3B | O60391 | 6/20 | 0.71 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.71 |
| ▸ | GRIN2C | Q14957 | 6/20 | 0.71 |
| ▸ | GRIN3A | Q8TCU5 | 6/20 | 0.71 |
| ▸ | LMNA | P02545 | 4/20 | 0.71 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.71 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.71 |
| ▸ | SLC47A1 | Q96FL8 | 2/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | STAT6 | P42226 | 1/20 | 0.71 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.71 |
| ▸ | THRB | P10828 | 2/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13558671 | 0.86 | GRIN1 (0.60) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL10890351 | 0.86 | GRIN1 (0.60) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL6854902 | 0.85 | LMNA (0.52) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL1558149 | 0.84 | GRIN1 (0.57) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL12367863 | 0.84 | GRIN1 (0.57) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL12758972 | 0.84 | GRIN1 (0.57) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL12832468 | 0.84 | GRIN1 (0.57) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL1497420 | 0.84 | GRIN1 (0.57) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL1497404 | 0.84 | GRIN1 (0.57) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL12832299 | 0.84 | GRIN1 (0.57) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021203048-A1 | NOVEL 2-PYRIMIDONE ANALOGS AS POTENT ANTIVIRAL AGENTS AGAINST ALPHAVIRUSES | SOUTHERN RESEARCH INSTITUTE (US) | 2021-10-07 | — | — | WO | disclosed |
| WO-2020263790-A1 | OLEFIN POLYMERIZATION CATALYSTS BEARING A THIAZOLE OR IMIDAZOLE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-12-30 | — | — | WO | disclosed |
| EP-3564240-A1 | PIPERIDINE INTERMEDIATES | Purdue Pharma L.P. (US) | 2019-11-06 | — | — | EP | disclosed |
| US-20180170862-A1 | PROTEIN TYROSINE PHOSPHATASES OR SHP2 INHIBITORS AND USES THEREOF | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION | 2018-06-21 | — | — | US | disclosed |
| US-20180170861-A1 | SMALL MOLECULE INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES AND USED THEREOF | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION | 2018-06-21 | — | — | US | disclosed |
| EP-3333917-A1 | ORGANIC THIN FILM TRANSISTOR, METHOD FOR MANUFACTURING ORGANIC THIN FILM TRANSISTOR, MATERIAL FOR ORGANIC THIN FILM TRANSISTORS, COMPOSITION FOR ORGANIC THIN FILM TRANSISTORS, ORGANIC SEMICONDUCTOR FILM, AND COMPOUND | FUJIFILM Corporation (JP) | 2018-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180170861-A1 | SMALL MOLECULE INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES AND USED THEREOF | PTPA, EPM2A, PTPRA | GRIN1 2912/4885GRIN2A 759/4885GRIN2D 3197/4885 |
| US-20180170862-A1 | PROTEIN TYROSINE PHOSPHATASES OR SHP2 INHIBITORS AND USES THEREOF | PTPA, PTPRA, PTPRCAP | GRIN1 2652/4885GRIN2A 761/4885GRIN2D 3201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.