Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850156 | 0.90 | CYP3A4 (0.53) | SMN1; SMN2L3MBTL1HPGDMAPTCYP1A2 | |
| SCHEMBL20245315 | 0.82 | HSD17B3 (0.65) | SMN1; SMN2L3MBTL1HPGDRAB9AKDM4E | |
| SCHEMBL3733726 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2L3MBTL1HPGDMAPTFFAR1 | |
| SCHEMBL20245318 | 0.81 | ALDH1A1 (0.50) | SMN1; SMN2L3MBTL1HPGDMAPTLMNA | |
| SCHEMBL7327582 | 0.81 | ALDH1A1 (0.55) | SMN1; SMN2HDAC1ALDH1A1HDAC8POLB | |
| SCHEMBL20245203 | 0.81 | HDAC1 (0.49) | HPGDMAPTHDAC1ALDH1A1HDAC8 | |
| SCHEMBL7434935 | 0.80 | SMN1; SMN2 (0.59) | SMN1; SMN2L3MBTL1HPGDMAPTFFAR1 | |
| SCHEMBL11095908 | 0.79 | SMN1; SMN2 (0.67) | SMN1; SMN2L3MBTL1HPGDMAPTFFAR1 | |
| SCHEMBL7021562 | 0.79 | EPHX2 (0.60) | HPGDHDAC1HDAC8KMT2AMEN1 | |
| SCHEMBL20245173 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2HPGDMAPTLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3332645-A1 | USE OF SUBSTITUTED PYRIMIDINE DIONES OR THEIR SALTS AS AGENTS TO COMBAT ABIOTIC PLANT STRESS | Bayer Cropscience AG (DE) | 2018-06-13 | — | — | EP | disclosed |