Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20246927 | 0.82 | ALDH1A1 (0.30) | ALDH1A1KMT2A | |
| SCHEMBL20246981 | 0.82 | HSP90AA1 (0.35) | — | |
| SCHEMBL431632 | 0.74 | GPR35 (0.41) | ALDH1A1KMT2A | |
| SCHEMBL20246925 | 0.74 | ATM (0.33) | ALDH1A1 | |
| SCHEMBL1946039 | 0.66 | ALDH1A1 (0.33) | ALDH1A1KMT2A | |
| SCHEMBL2548910 | 0.62 | CYP19A1 (0.50) | ALDH1A1KMT2A | |
| SCHEMBL15556071 | 0.62 | ALDH1A1 (0.57) | ALDH1A1KMT2A | |
| SCHEMBL25886876 | 0.61 | HSP90AA1 (0.51) | ALDH1A1KMT2A | |
| SCHEMBL22890476 | 0.60 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL2785910 | 0.60 | ALDH1A1 (0.56) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595982-B1 | PROTEIN KINASE C INHIBITORS AND USES THEREOF | RIGEL PHARMACEUTICALS INC (US) | 2018-06-13 | — | — | EP | disclosed |