Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.60 |
| ▸ | KIF11 | P52732 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13560649 | 0.86 | KIF11 (0.56) | MEN1KMT2APOLBNPC1ABCB1 | |
| SCHEMBL13267003 | 0.86 | KIF11 (0.67) | MEN1KMT2APOLBNPC1ABCB1 | |
| SCHEMBL29726988 | 0.86 | KIF11 (0.67) | MEN1KMT2APOLBNPC1ABCB1 | |
| SCHEMBL12086512 | 0.84 | KIF11 (0.51) | MEN1KMT2APOLBNPC1ABCB1 | |
| SCHEMBL14116119 | 0.83 | KIF11 (0.72) | MEN1KMT2APOLBNPC1ABCB1 | |
| SCHEMBL13412884 | 0.81 | MEN1 (0.65) | MEN1KMT2APOLBNPC1ABCB1 | |
| SCHEMBL13933160 | 0.80 | NPC1 (0.81) | MEN1KMT2APOLBNPC1KIF11 | |
| SCHEMBL17616019 | 0.80 | MEN1 (1.00) | MEN1KMT2APOLBNPC1ABCB1 | |
| SCHEMBL21563915 | 0.78 | MEN1 (0.61) | MEN1KMT2APOLBNPC1ABCB1 | |
| SCHEMBL276094 | 0.77 | NPC1 (0.76) | MEN1KMT2APOLBNPC1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252605-B1 | LABELLED ANALOGUES OF HALOBENZAMIDES AS MULTIMODAL RADIOPHARMACEUTICALS AND THEIR PRECURSORS | INST NAT SANTE RECH MED (FR) | 2018-06-13 | — | — | EP | disclosed |