Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 6/20 | 0.40 |
| ▸ | CA5A | P35218 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CA3 | P07451 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA6 | P23280 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2214769 | 0.86 | CYP19A1 (0.52) | KMT2AHTTGAACA2CA5A | |
| SCHEMBL816810 | 0.86 | HTT (0.48) | KMT2AHTTGAACA2CA5A | |
| SCHEMBL2055461 | 0.79 | ALDH1A1 (0.46) | KMT2AHTTGAACA2CA5A | |
| SCHEMBL15122462 | 0.78 | KMT2A (0.42) | KMT2AHTTGAACA2CA5A | |
| SCHEMBL2820707 | 0.78 | ACP1 (0.43) | KMT2AHTTGAACA2CA5A | |
| SCHEMBL11822050 | 0.77 | CYP19A1 (0.55) | KMT2AHTTALDH1A1CYP19A1MEN1 | |
| SCHEMBL3182658 | 0.77 | CYP19A1 (0.62) | KMT2AHTTALDH1A1CYP19A1MEN1 | |
| SCHEMBL23113418 | 0.74 | HTT (0.42) | KMT2AHTTGAACA2CA5A | |
| SCHEMBL16829550 | 0.74 | PTGS1 (0.46) | KMT2AHTTGAAALDH1A1MEN1 | |
| SCHEMBL2310139 | 0.74 | VCAM1 (0.65) | KMT2AHTTGAACA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018104307-A1 | AROMATIC SULFONAMIDE DERIVATIVES AND THEIR USE AS ANATAGON I STS OR NEGATIVE ALLOSTERIC MODULATORS OF P2X4 | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-06-14 | — | — | WO | disclosed |