Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20249094 | 0.82 | PTGDR2 (0.51) | PTGDR2HSD17B10NPC1NFKB1RAB9A | |
| SCHEMBL2562334 | 0.78 | HPGD (0.57) | PTGDR2HSD17B10NPC1NFKB1RAB9A | |
| SCHEMBL29950848 | 0.78 | KMT2A (0.62) | PTGDR2HSD17B10NPC1NFKB1RAB9A | |
| SCHEMBL22588977 | 0.77 | PTGDR2 (0.55) | PTGDR2HSD17B10NPC1NFKB1RAB9A | |
| SCHEMBL2552236 | 0.75 | HPGD (0.67) | PTGDR2HSD17B10NPC1NFKB1RAB9A | |
| SCHEMBL22602534 | 0.75 | TSHR (0.48) | PTGDR2HSD17B10NPC1NFKB1RAB9A | |
| SCHEMBL15332808 | 0.75 | PTGDR2 (0.59) | PTGDR2HSD17B10NPC1NFKB1RAB9A | |
| SCHEMBL22602544 | 0.74 | TSHR (0.47) | PTGDR2HSD17B10NPC1NFKB1RAB9A | |
| SCHEMBL29410428 | 0.74 | TSHR (0.47) | PTGDR2HSD17B10NPC1NFKB1RAB9A | |
| SCHEMBL2553005 | 0.74 | KDM4E (0.61) | PTGDR2HSD17B10NPC1NFKB1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020217250-A2 | METHOD FOR METAL-FREE PURIFICATION OF PROTEIN FROM A PROTEIN MIXTURE OR A CELL LYSATE WITH THE N-TERMINUS GLYCINE TAGGING | Indian Institute Of Science Education And Research Bhopal (IN) | 2020-10-29 | — | — | WO | disclosed |
| WO-2018104962-A1 | HEMIAMINAL-TAG FOR PROTEIN LABELING AND PURIFICATION | Indian Institute Of Science Education And Research Bhopal (IN) | 2018-06-14 | — | — | WO | disclosed |