Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15332808 | 0.92 | PTGDR2 (0.59) | KMT2APTGDR2HSD17B10TSHRNPC1 | |
| SCHEMBL2562334 | 0.87 | HPGD (0.57) | KMT2APTGDR2HSD17B10TSHRRECQL | |
| SCHEMBL29955221 | 0.86 | PTGDR2 (0.62) | KMT2APTGDR2HSD17B10TSHRNPC1 | |
| SCHEMBL22588977 | 0.85 | PTGDR2 (0.55) | KMT2APTGDR2HSD17B10TSHRRECQL | |
| SCHEMBL7365741 | 0.85 | PTGDR2 (0.60) | KMT2APTGDR2HSD17B10TSHRNPC1 | |
| SCHEMBL2552236 | 0.84 | HPGD (0.67) | PTGDR2HSD17B10TSHRNPC1NFKB1 | |
| SCHEMBL29958062 | 0.84 | HSD17B10 (0.51) | KMT2AHSD17B10TSHRRECQLNPC1 | |
| SCHEMBL2555017 | 0.83 | MAPT (0.56) | KMT2APTGDR2HSD17B10TSHRNPC1 | |
| SCHEMBL29954513 | 0.82 | NPSR1 (0.52) | KMT2ATSHRNPC1RAB9AHPGD | |
| SCHEMBL10869056 | 0.81 | KMT2A (0.65) | KMT2AHSD17B10TSHRRECQLHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |